Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery
BackgroundPostoperative nausea and vomiting (PONV) and postoperative pain are among the most common side-effects of surgery. Many factors, such as a change in the level of sex hormones, are reported to affect these complications. This study aimed to evaluate the probable effects of the menopause on...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Anesthesiologists
2015-12-01
|
| Series: | Korean Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://ekja.org/upload/pdf/kjae-68-581.pdf |
| _version_ | 1818720478886363136 |
|---|---|
| author | Sepideh Vahabi Abolfazl Abaszadeh Fatemeh Yari Nazanin Yousefi |
| author_facet | Sepideh Vahabi Abolfazl Abaszadeh Fatemeh Yari Nazanin Yousefi |
| author_sort | Sepideh Vahabi |
| collection | DOAJ |
| description | BackgroundPostoperative nausea and vomiting (PONV) and postoperative pain are among the most common side-effects of surgery. Many factors, such as a change in the level of sex hormones, are reported to affect these complications. This study aimed to evaluate the probable effects of the menopause on PONV and postoperative pain.MethodsProspective study, in which a total number of 144 female patients undergoing cystocele or rectocele repair surgery under standardized spinal anesthesia were included. Patients were divided into two equally sized sample groups of pre- and postmenopausal women (n = 72). The occurrence of PONV, the severity of pain as assessed by visual analog scale (VAS) pain score, and the quantity of morphine and metoclopramide required were recorded at 2, 4, 6, 12, 18 and 24 h after surgery.ResultsThe mean VAS pain score and the mean quantity of morphine required was higher among premenopausal women (P = 0.006). Moreover, these patients required more morphine for their pain management during the first 24 h after surgery compared to postmenopausal women (P < 0.0001). No difference was observed between the two groups regarding the incidence of PONV (P = 0.09 and P = 1.00 for nausea and vomiting, respectively) and the mean amount of metoclopramide required (P = 0.38).ConclusionsPremenopausal women are more likely to suffer from postoperative pain after cystocele and rectocele repair surgery. Further studies regarding the measurement of hormonal changes among surgical patients in both pre- and postmenopausal women are recommended to evaluate the effects on PONV and postoperative pain. |
| first_indexed | 2024-12-17T20:23:29Z |
| format | Article |
| id | doaj.art-8cc97f58b31d413884efe15b42b1263e |
| institution | Directory Open Access Journal |
| issn | 2005-6419 2005-7563 |
| language | English |
| last_indexed | 2024-12-17T20:23:29Z |
| publishDate | 2015-12-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Korean Journal of Anesthesiology |
| spelling | doaj.art-8cc97f58b31d413884efe15b42b1263e2022-12-21T21:33:53ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632015-12-0168658158510.4097/kjae.2015.68.6.5818128Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgerySepideh Vahabi0Abolfazl Abaszadeh1Fatemeh Yari2Nazanin Yousefi3Department of Anesthesiology and Critical Care, Lorestan University of Medical Science, Khoramabad, Iran.Department of Anesthesiology and Critical Care, Lorestan University of Medical Science, Khoramabad, Iran.Department of Anesthesiology and Critical Care, Lorestan University of Medical Science, Khoramabad, Iran.Department of Anesthesiology and Critical Care, Lorestan University of Medical Science, Khoramabad, Iran.BackgroundPostoperative nausea and vomiting (PONV) and postoperative pain are among the most common side-effects of surgery. Many factors, such as a change in the level of sex hormones, are reported to affect these complications. This study aimed to evaluate the probable effects of the menopause on PONV and postoperative pain.MethodsProspective study, in which a total number of 144 female patients undergoing cystocele or rectocele repair surgery under standardized spinal anesthesia were included. Patients were divided into two equally sized sample groups of pre- and postmenopausal women (n = 72). The occurrence of PONV, the severity of pain as assessed by visual analog scale (VAS) pain score, and the quantity of morphine and metoclopramide required were recorded at 2, 4, 6, 12, 18 and 24 h after surgery.ResultsThe mean VAS pain score and the mean quantity of morphine required was higher among premenopausal women (P = 0.006). Moreover, these patients required more morphine for their pain management during the first 24 h after surgery compared to postmenopausal women (P < 0.0001). No difference was observed between the two groups regarding the incidence of PONV (P = 0.09 and P = 1.00 for nausea and vomiting, respectively) and the mean amount of metoclopramide required (P = 0.38).ConclusionsPremenopausal women are more likely to suffer from postoperative pain after cystocele and rectocele repair surgery. Further studies regarding the measurement of hormonal changes among surgical patients in both pre- and postmenopausal women are recommended to evaluate the effects on PONV and postoperative pain.http://ekja.org/upload/pdf/kjae-68-581.pdfmenopausepostoperative nausea and vomitingpostoperative pain |
| spellingShingle | Sepideh Vahabi Abolfazl Abaszadeh Fatemeh Yari Nazanin Yousefi Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery Korean Journal of Anesthesiology menopause postoperative nausea and vomiting postoperative pain |
| title | Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery |
| title_full | Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery |
| title_fullStr | Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery |
| title_full_unstemmed | Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery |
| title_short | Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery |
| title_sort | postoperative pain nausea and vomiting among pre and postmenopausal women undergoing cystocele and rectocele repair surgery |
| topic | menopause postoperative nausea and vomiting postoperative pain |
| url | http://ekja.org/upload/pdf/kjae-68-581.pdf |
| work_keys_str_mv | AT sepidehvahabi postoperativepainnauseaandvomitingamongpreandpostmenopausalwomenundergoingcystoceleandrectocelerepairsurgery AT abolfazlabaszadeh postoperativepainnauseaandvomitingamongpreandpostmenopausalwomenundergoingcystoceleandrectocelerepairsurgery AT fatemehyari postoperativepainnauseaandvomitingamongpreandpostmenopausalwomenundergoingcystoceleandrectocelerepairsurgery AT nazaninyousefi postoperativepainnauseaandvomitingamongpreandpostmenopausalwomenundergoingcystoceleandrectocelerepairsurgery |