Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model.
The role of astrocytes in Parkinson's disease is still not well understood. This work studied the astrocytic response to the dopaminergic denervation. Rats were injected in the lateral ventricles with 6-hydroxydopamine (25μg), inducing a dopaminergic denervation of the striatum not accompanied...
Main Authors: | Ingrid Morales, Alberto Sanchez, Clara Rodriguez-Sabate, Manuel Rodriguez |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5640218?pdf=render |
Similar Items
-
Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris
by: Ingrid Morales, et al.
Published: (2021-11-01) -
Astrocytes, a Promising Opportunity to Control the Progress of Parkinson’s Disease
by: Alberto Sanchez, et al.
Published: (2021-09-01) -
Experimental parkinsonism in modeling striatal astrocyte damage
by: Alla V. Stavrovskaya, et al.
Published: (2019-09-01) -
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease.
by: Hu, M, et al.
Published: (2006) -
Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease
by: Jana Ivanidze, et al.
Published: (2020-09-01)