Overcoming PARP Inhibitor and Platinum Resistance with WEE1 Inhibitors in Ovarian Cancer
Poly (ADP-ribose) polymerase inhibitors (PARPi) have transformed the treatment of high-grade epithelial ovarian cancer (EOC), with demonstrated efficacy in the recurrent as well as newly diagnosed disease. However, women with EOC inevitably acquire resistance to both platinum chemotherapy and PARPi....
Main Author: | Ilaria Colombo |
---|---|
Format: | Article |
Language: | English |
Published: |
THE HEALTHBOOK COMPANY LTD.
2021-10-01
|
Series: | healthbook TIMES. Oncology Hematology |
Online Access: | https://doi.org/10.36000/hbT.OH.2021.09.047 |
Similar Items
-
Overcoming Platinum and PARP-Inhibitor Resistance in Ovarian Cancer
by: Michelle McMullen, et al.
Published: (2020-06-01) -
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
by: Hyoung Kim, et al.
Published: (2020-07-01) -
Advances in ATM, ATR, WEE1, and CHK1/2 inhibitors in the treatment of PARP inhibitor-resistant ovarian cancer
by: Qin Tang, et al.
Published: (2023-12-01) -
Overcoming resistance to PARP inhibitor in epithelial ovarian cancer, are we ready?
by: Isabelle Ray-Coquard, et al.
Published: (2020-11-01) -
PARP Inhibitor in Platinum-Resistant Ovarian Cancer: Single-Center Real-World Experience
by: Amit Agarwal, et al.
Published: (2021-12-01)