Severe Clostridium diffi cile infection after liver and kidney transplantation

Recent statistics have shown increased rates of morbidity and mortality from Clostridium difficile infection worldwide. This problem is mainly typical for surgical patients and is associated with an antibiotic therapy and a prolonged hospital stay. Recipients of solid organs are at a high risk of de...

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Main Authors: K. Yu. Kokina, Yu. O. Malinovskaya, A. B. Sidorenko, Ya. G. Moisyuk
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2019-12-01
Series:Трансплантология (Москва)
Subjects:
Online Access:https://www.jtransplantologiya.ru/jour/article/view/464
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author K. Yu. Kokina
Yu. O. Malinovskaya
A. B. Sidorenko
Ya. G. Moisyuk
author_facet K. Yu. Kokina
Yu. O. Malinovskaya
A. B. Sidorenko
Ya. G. Moisyuk
author_sort K. Yu. Kokina
collection DOAJ
description Recent statistics have shown increased rates of morbidity and mortality from Clostridium difficile infection worldwide. This problem is mainly typical for surgical patients and is associated with an antibiotic therapy and a prolonged hospital stay. Recipients of solid organs are at a high risk of developing severe forms of C. difficile infection due to immunosupression. Existing recommendations for the treatment of C. difficile infection are based on the severity of the disease and do not consider patients after liver transplantation. The aim of this work is to determine an actual tactics for the diagnosis and treatment of C. difficile in organ recipients in clinical practice.
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spelling doaj.art-8cd3e910729b4383be28ca5215a674432023-09-03T13:24:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092019-12-0111432032910.23873/2074-0506-2019-11-4-320-329428Severe Clostridium diffi cile infection after liver and kidney transplantationK. Yu. Kokina0Yu. O. Malinovskaya1A. B. Sidorenko2Ya. G. Moisyuk3ГБУЗ МО МОНИКИ им. М.Ф. ВладимирскогоГБУЗ МО МОНИКИ им. М.Ф. ВладимирскогоГБУЗ МО МОНИКИ им. М.Ф. ВладимирскогоГБУЗ МО МОНИКИ им. М.Ф. ВладимирскогоRecent statistics have shown increased rates of morbidity and mortality from Clostridium difficile infection worldwide. This problem is mainly typical for surgical patients and is associated with an antibiotic therapy and a prolonged hospital stay. Recipients of solid organs are at a high risk of developing severe forms of C. difficile infection due to immunosupression. Existing recommendations for the treatment of C. difficile infection are based on the severity of the disease and do not consider patients after liver transplantation. The aim of this work is to determine an actual tactics for the diagnosis and treatment of C. difficile in organ recipients in clinical practice.https://www.jtransplantologiya.ru/jour/article/view/464clostridium difficileпсевдомембранозный колиттрансплантация солидных органов
spellingShingle K. Yu. Kokina
Yu. O. Malinovskaya
A. B. Sidorenko
Ya. G. Moisyuk
Severe Clostridium diffi cile infection after liver and kidney transplantation
Трансплантология (Москва)
clostridium difficile
псевдомембранозный колит
трансплантация солидных органов
title Severe Clostridium diffi cile infection after liver and kidney transplantation
title_full Severe Clostridium diffi cile infection after liver and kidney transplantation
title_fullStr Severe Clostridium diffi cile infection after liver and kidney transplantation
title_full_unstemmed Severe Clostridium diffi cile infection after liver and kidney transplantation
title_short Severe Clostridium diffi cile infection after liver and kidney transplantation
title_sort severe clostridium diffi cile infection after liver and kidney transplantation
topic clostridium difficile
псевдомембранозный колит
трансплантация солидных органов
url https://www.jtransplantologiya.ru/jour/article/view/464
work_keys_str_mv AT kyukokina severeclostridiumdifficileinfectionafterliverandkidneytransplantation
AT yuomalinovskaya severeclostridiumdifficileinfectionafterliverandkidneytransplantation
AT absidorenko severeclostridiumdifficileinfectionafterliverandkidneytransplantation
AT yagmoisyuk severeclostridiumdifficileinfectionafterliverandkidneytransplantation