Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1

Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1

The most common type of kidney cancer in adults is renal cell carcinoma (RCC), which accounts for approximately 90% of cases. RCC is a variant disease with numerous subtypes; the most common subtype is clear cell RCC (ccRCC, 75%), followed by papillary RCC (pRCC, 10%) and chromophobe RCC (chRCC, 5%)...

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Bibliographic Details
Main Authors: Seong Hwi Hong, Hyun Ji Hwang, Da Hyeon Son, Eun Song Kim, Sung Yul Park, Young Eun Yoon
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:FEBS Open Bio
Subjects:
EZH2
Hippo pathway
LATS1
renal cell carcinoma
tazemetostat
Online Access:https://doi.org/10.1002/2211-5463.13579

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