Association of cortical and subcortical microstructure with disease severity: impact on cognitive decline and language impairments in frontotemporal lobar degeneration

Association of cortical and subcortical microstructure with disease severity: impact on cognitive decline and language impairments in frontotemporal lobar degeneration

Abstract Background Cortical and subcortical microstructural modifications are critical to understanding the pathogenic changes in frontotemporal lobar degeneration (FTLD) subtypes. In this study, we investigated cortical and subcortical microstructure underlying cognitive and language impairments a...

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Bibliographic Details
Main Authors: Wencai Ding, Peng Ren, Liye Yi, Yao Si, Fan Yang, Zhipeng Li, Hongbo Bao, Shi Yan, Xinyu Zhang, Siyang Li, Xia Liang, Lifen Yao, for the Frontotemporal Lobar Degeneration Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
Frontotemporal lobar degeneration
Microstructure
Diffusion
Mean diffusivity
Fractional anisotropy
Biomarker
Online Access:https://doi.org/10.1186/s13195-023-01208-7

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