PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma

PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma

Proteasome 26S subunit ATPase 2 (PSMC2) plays a pathogenic role in various cancers. However, its function and molecular mechanism in hepatocellular carcinoma (HCC) remain unknown. In this study, tissue microarray (TMA) analysis showed that PSMC2 is highly expressed in HCC tumors and correlates with...

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Bibliographic Details
Main Authors: Yiwei Liu, Hairong Chen, Xiangcheng Li, Feng Zhang, Lianbao Kong, Xuehao Wang, Jin Bai, Xiaofeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
PSMC2
hepatocellular carcinoma
p21
cell proliferation
carcinogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.607021/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.607021/full

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