Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya

Molecular surveillance of drug resistance markers through time provides crucial information on genomic adaptations, especially in parasite populations exposed to changing drug pressures. To assess temporal trends of established genotypes associated with tolerance to clinically important antimalarial...

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Bibliographic Details
Main Authors: John Okombo, Alice W. Kamau, Kevin Marsh, Colin J. Sutherland, Lynette Isabella Ochola-Oyier
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Antimalarial policy
Drug resistance
Microsatellites
pfcrt
pfmdr1
pfdhfr
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320714000165

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