An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network

COVID-19 has spread rapidly across the world since late 2019. As of December, 2021, there are over 250 million documented COVID-19 cases and over 5 million deaths worldwide, which have caused businesses, schools, and government operations to shut down. The most common method of detecting COVID-19 is...

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Main Authors: Gabriel Ackall, Mohammed Elmzoudi, Richard Yuan, Cuixian Chen
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Technologies
Subjects:
Online Access:https://www.mdpi.com/2227-7080/9/4/98
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author Gabriel Ackall
Mohammed Elmzoudi
Richard Yuan
Cuixian Chen
author_facet Gabriel Ackall
Mohammed Elmzoudi
Richard Yuan
Cuixian Chen
author_sort Gabriel Ackall
collection DOAJ
description COVID-19 has spread rapidly across the world since late 2019. As of December, 2021, there are over 250 million documented COVID-19 cases and over 5 million deaths worldwide, which have caused businesses, schools, and government operations to shut down. The most common method of detecting COVID-19 is the RT-PCR swab test, which suffers from a high false-negative rate and a very slow turnaround for results, often up to two weeks. Because of this, specialists often manually review X-ray images of the lungs to detect the presence of COVID-19 with up to 97% accuracy. Neural network algorithms greatly accelerate this review process, analyzing hundreds of X-rays in seconds. Using the Cohen COVID-19 X-ray Database and the NIH ChestX-ray8 Database, we trained and constructed the xRGM-NET convolutional neural network (CNN) to detect COVID-19 in X-ray scans of the lungs. To further aid medical professionals in the manual review of X-rays, we implemented the CNN activation mapping technique Score-CAM, which generates a heat map over an X-ray to illustrate which areas in the scan are most influential over the ultimate diagnosis. xRGM-NET achieved an overall classification accuracy of 97% with a sensitivity of 94% and specificity of 97%. Lightweight models like xRGM-NET can serve to improve the efficiency and accuracy of COVID-19 detection in developing countries or rural areas. In this paper, we report on our model and methods that were developed as part of a STEM enrichment summer program for high school students. We hope that our model and methods will allow other researchers to create lightweight and accurate models as more COVID-19 X-ray scans become available.
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spelling doaj.art-8cdbd753a25240a8aba8b20b307ec8a22023-11-23T10:48:21ZengMDPI AGTechnologies2227-70802021-12-01949810.3390/technologies9040098An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural NetworkGabriel Ackall0Mohammed Elmzoudi1Richard Yuan2Cuixian Chen3School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USADepartment of Computer Science, Duke University, Durham, NC 27708, USASchool of Humanities and Sciences, Stanford University, Stanford, CA 94305, USADepartment of Mathematics and Statistics, University of North Carolina Wilmington, Wilmington, NC 28407, USACOVID-19 has spread rapidly across the world since late 2019. As of December, 2021, there are over 250 million documented COVID-19 cases and over 5 million deaths worldwide, which have caused businesses, schools, and government operations to shut down. The most common method of detecting COVID-19 is the RT-PCR swab test, which suffers from a high false-negative rate and a very slow turnaround for results, often up to two weeks. Because of this, specialists often manually review X-ray images of the lungs to detect the presence of COVID-19 with up to 97% accuracy. Neural network algorithms greatly accelerate this review process, analyzing hundreds of X-rays in seconds. Using the Cohen COVID-19 X-ray Database and the NIH ChestX-ray8 Database, we trained and constructed the xRGM-NET convolutional neural network (CNN) to detect COVID-19 in X-ray scans of the lungs. To further aid medical professionals in the manual review of X-rays, we implemented the CNN activation mapping technique Score-CAM, which generates a heat map over an X-ray to illustrate which areas in the scan are most influential over the ultimate diagnosis. xRGM-NET achieved an overall classification accuracy of 97% with a sensitivity of 94% and specificity of 97%. Lightweight models like xRGM-NET can serve to improve the efficiency and accuracy of COVID-19 detection in developing countries or rural areas. In this paper, we report on our model and methods that were developed as part of a STEM enrichment summer program for high school students. We hope that our model and methods will allow other researchers to create lightweight and accurate models as more COVID-19 X-ray scans become available.https://www.mdpi.com/2227-7080/9/4/98COVID-19RT-PCR swab testconvolutional neural network (CNN)X-rayactivation mappingscore-CAM
spellingShingle Gabriel Ackall
Mohammed Elmzoudi
Richard Yuan
Cuixian Chen
An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
Technologies
COVID-19
RT-PCR swab test
convolutional neural network (CNN)
X-ray
activation mapping
score-CAM
title An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
title_full An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
title_fullStr An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
title_full_unstemmed An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
title_short An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network
title_sort exploration into the detection of covid 19 from chest x ray scans using the xrgm net convolutional neural network
topic COVID-19
RT-PCR swab test
convolutional neural network (CNN)
X-ray
activation mapping
score-CAM
url https://www.mdpi.com/2227-7080/9/4/98
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