Secondary metabolites and biodiversity of actinomycetes
Abstract Background The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and biological processes. Main body Actinomycete...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-05-01
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| Series: | Journal of Genetic Engineering and Biotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43141-021-00156-9 |
| _version_ | 1797204400978001920 |
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| author | Manal Selim Mohamed Selim Sayeda Abdelrazek Abdelhamid Sahar Saleh Mohamed |
| author_facet | Manal Selim Mohamed Selim Sayeda Abdelrazek Abdelhamid Sahar Saleh Mohamed |
| author_sort | Manal Selim Mohamed Selim |
| collection | DOAJ |
| description | Abstract Background The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and biological processes. Main body Actinomycetes are widely distributed in natural ecosystem habitats such as soil, rhizosphere soil, actinmycorrhizal plants, hypersaline soil, limestone, freshwater, marine, sponges, volcanic cave—hot spot, desert, air, insects gut, earthworm castings, goat feces, and endophytic actinomycetes. The most important features of microbial bioactive compounds are that they have specific microbial producers: their diverse bioactivities and their unique chemical structures. Actinomycetes represent a source of biologically active secondary metabolites like antibiotics, biopesticide agents, plant growth hormones, antitumor compounds, antiviral agents, pharmacological compounds, pigments, enzymes, enzyme inhibitors, anti-inflammatory compounds, single-cell protein feed, and biosurfactant. Short conclusions Further highlight that compounds derived from actinobacteria can be applied in a wide range of industrial applications in biomedicines and the ecological habitat is under-explored and yet to be investigated for unknown, rare actinomycetes diversity. |
| first_indexed | 2024-04-24T08:34:38Z |
| format | Article |
| id | doaj.art-8cdbdee272b04c02a90a0dd264362d1c |
| institution | Directory Open Access Journal |
| issn | 2090-5920 |
| language | English |
| last_indexed | 2024-04-24T08:34:38Z |
| publishDate | 2021-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Genetic Engineering and Biotechnology |
| spelling | doaj.art-8cdbdee272b04c02a90a0dd264362d1c2024-04-16T18:10:04ZengElsevierJournal of Genetic Engineering and Biotechnology2090-59202021-05-0119111310.1186/s43141-021-00156-9Secondary metabolites and biodiversity of actinomycetesManal Selim Mohamed Selim0Sayeda Abdelrazek Abdelhamid1Sahar Saleh Mohamed2Microbial Biotechnology Department—Genetic Engineering Division, National Research CentreMicrobial Biotechnology Department—Genetic Engineering Division, National Research CentreMicrobial Biotechnology Department—Genetic Engineering Division, National Research CentreAbstract Background The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and biological processes. Main body Actinomycetes are widely distributed in natural ecosystem habitats such as soil, rhizosphere soil, actinmycorrhizal plants, hypersaline soil, limestone, freshwater, marine, sponges, volcanic cave—hot spot, desert, air, insects gut, earthworm castings, goat feces, and endophytic actinomycetes. The most important features of microbial bioactive compounds are that they have specific microbial producers: their diverse bioactivities and their unique chemical structures. Actinomycetes represent a source of biologically active secondary metabolites like antibiotics, biopesticide agents, plant growth hormones, antitumor compounds, antiviral agents, pharmacological compounds, pigments, enzymes, enzyme inhibitors, anti-inflammatory compounds, single-cell protein feed, and biosurfactant. Short conclusions Further highlight that compounds derived from actinobacteria can be applied in a wide range of industrial applications in biomedicines and the ecological habitat is under-explored and yet to be investigated for unknown, rare actinomycetes diversity.https://doi.org/10.1186/s43141-021-00156-9ActinomycetesBiodiversityBioactive compoundSecondary metabolites |
| spellingShingle | Manal Selim Mohamed Selim Sayeda Abdelrazek Abdelhamid Sahar Saleh Mohamed Secondary metabolites and biodiversity of actinomycetes Journal of Genetic Engineering and Biotechnology Actinomycetes Biodiversity Bioactive compound Secondary metabolites |
| title | Secondary metabolites and biodiversity of actinomycetes |
| title_full | Secondary metabolites and biodiversity of actinomycetes |
| title_fullStr | Secondary metabolites and biodiversity of actinomycetes |
| title_full_unstemmed | Secondary metabolites and biodiversity of actinomycetes |
| title_short | Secondary metabolites and biodiversity of actinomycetes |
| title_sort | secondary metabolites and biodiversity of actinomycetes |
| topic | Actinomycetes Biodiversity Bioactive compound Secondary metabolites |
| url | https://doi.org/10.1186/s43141-021-00156-9 |
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