Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT
<p>Abstract</p> <p>Background</p> <p>Real-time perfusion (RTP) contrast echocardiography can be used during adenosine stress echocardiography (ASE) to evaluate myocardial ischemia. We compared two different types of RTP power modulation techniques, angiomode (AM) and hi...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-04-01
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| Series: | Cardiovascular Ultrasound |
| Online Access: | http://www.cardiovascularultrasound.com/content/7/1/19 |
| _version_ | 1819058200915214336 |
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| author | Thorsson Ola Kitlinski Mariusz Dencker Magnus Winter Reidar Shahgaldi Kambiz Gudmundsson Petri Ljunggren Lennart Willenheimer Ronnie B |
| author_facet | Thorsson Ola Kitlinski Mariusz Dencker Magnus Winter Reidar Shahgaldi Kambiz Gudmundsson Petri Ljunggren Lennart Willenheimer Ronnie B |
| author_sort | Thorsson Ola |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Real-time perfusion (RTP) contrast echocardiography can be used during adenosine stress echocardiography (ASE) to evaluate myocardial ischemia. We compared two different types of RTP power modulation techniques, angiomode (AM) and high-resolution grayscale (HR), with <sup>99m</sup>Tc-tetrofosmin single-photon emission computed tomography (SPECT) for the detection of myocardial ischemia.</p> <p>Methods</p> <p>Patients with known or suspected coronary artery disease (CAD), admitted to SPECT, were prospectively invited to participate. Patients underwent RTP imaging (SONOS 5500) using AM and HR during Sonovue<sup>® </sup>infusion, before and throughout the adenosine stress, also used for SPECT. Analysis of myocardial perfusion and wall motion by RTP-ASE were done for AM and HR at different time points, blinded to one another and to SPECT. Each segment was attributed to one of the three main coronary vessel areas of interest.</p> <p>Results</p> <p>In 50 patients, 150 coronary areas were analyzed by SPECT and RTP-ASE AM and HR. SPECT showed evidence of ischemia in 13 out of 50 patients. There was no significant difference between AM and HR in detecting ischemia (p = 0.08). The agreement for AM and HR, compared to SPECT, was 93% and 96%, with Kappa values of 0.67 and 0.75, respectively (p < 0.001).</p> <p>Conclusion</p> <p>There was no significant difference between AM and HR in correctly detecting myocardial ischemia as judged by SPECT. This suggests that different types of RTP modalities give comparable data during RTP-ASE in patients with known or suspected CAD.</p> |
| first_indexed | 2024-12-21T13:51:26Z |
| format | Article |
| id | doaj.art-8cdbdf9087e44bb88d5da296721b6ecf |
| institution | Directory Open Access Journal |
| issn | 1476-7120 |
| language | English |
| last_indexed | 2024-12-21T13:51:26Z |
| publishDate | 2009-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Ultrasound |
| spelling | doaj.art-8cdbdf9087e44bb88d5da296721b6ecf2022-12-21T19:01:40ZengBMCCardiovascular Ultrasound1476-71202009-04-01711910.1186/1476-7120-7-19Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECTThorsson OlaKitlinski MariuszDencker MagnusWinter ReidarShahgaldi KambizGudmundsson PetriLjunggren LennartWillenheimer Ronnie B<p>Abstract</p> <p>Background</p> <p>Real-time perfusion (RTP) contrast echocardiography can be used during adenosine stress echocardiography (ASE) to evaluate myocardial ischemia. We compared two different types of RTP power modulation techniques, angiomode (AM) and high-resolution grayscale (HR), with <sup>99m</sup>Tc-tetrofosmin single-photon emission computed tomography (SPECT) for the detection of myocardial ischemia.</p> <p>Methods</p> <p>Patients with known or suspected coronary artery disease (CAD), admitted to SPECT, were prospectively invited to participate. Patients underwent RTP imaging (SONOS 5500) using AM and HR during Sonovue<sup>® </sup>infusion, before and throughout the adenosine stress, also used for SPECT. Analysis of myocardial perfusion and wall motion by RTP-ASE were done for AM and HR at different time points, blinded to one another and to SPECT. Each segment was attributed to one of the three main coronary vessel areas of interest.</p> <p>Results</p> <p>In 50 patients, 150 coronary areas were analyzed by SPECT and RTP-ASE AM and HR. SPECT showed evidence of ischemia in 13 out of 50 patients. There was no significant difference between AM and HR in detecting ischemia (p = 0.08). The agreement for AM and HR, compared to SPECT, was 93% and 96%, with Kappa values of 0.67 and 0.75, respectively (p < 0.001).</p> <p>Conclusion</p> <p>There was no significant difference between AM and HR in correctly detecting myocardial ischemia as judged by SPECT. This suggests that different types of RTP modalities give comparable data during RTP-ASE in patients with known or suspected CAD.</p>http://www.cardiovascularultrasound.com/content/7/1/19 |
| spellingShingle | Thorsson Ola Kitlinski Mariusz Dencker Magnus Winter Reidar Shahgaldi Kambiz Gudmundsson Petri Ljunggren Lennart Willenheimer Ronnie B Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT Cardiovascular Ultrasound |
| title | Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT |
| title_full | Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT |
| title_fullStr | Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT |
| title_full_unstemmed | Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT |
| title_short | Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT |
| title_sort | head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous spect |
| url | http://www.cardiovascularultrasound.com/content/7/1/19 |
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