Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term
ObjectivesTo assess neurocognitive function in adults born with low birthweight compared with controls and to explore associations between neurocognitive function and psychopathology in these groups.MethodsIn this prospective cohort study, one group born preterm with very low birthweight (VLBW: birt...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.1078232/full |
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| author | Siri Weider Astrid M. W. Lærum Astrid M. W. Lærum Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Solveig Klæbo Reitan Solveig Klæbo Reitan Stian Lydersen Ann Mari Brubakk Jon Skranes Jon Skranes Marit S. Indredavik |
| author_facet | Siri Weider Astrid M. W. Lærum Astrid M. W. Lærum Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Solveig Klæbo Reitan Solveig Klæbo Reitan Stian Lydersen Ann Mari Brubakk Jon Skranes Jon Skranes Marit S. Indredavik |
| author_sort | Siri Weider |
| collection | DOAJ |
| description | ObjectivesTo assess neurocognitive function in adults born with low birthweight compared with controls and to explore associations between neurocognitive function and psychopathology in these groups.MethodsIn this prospective cohort study, one group born preterm with very low birthweight (VLBW: birthweight <1,500 g, n = 53), one group born small for gestational age at term (SGA: birthweight <10th percentile, n = 63) and one term-born control group (birthweight ≥10th percentile, n = 81) were assessed with neurocognitive tests, diagnostic interviews, and self-report questionnaires at 26 years of age.ResultsThe VLBW group scored significantly below the control group on several neurocognitive measures, including IQ measures, psychomotor speed, verbal fluency, aspects of visual learning and memory, attention, social cognition, working memory and fine motor speed. The SGA group consistently scored at an intermediate level between the VLBW and the control group and had significantly lower scores than controls on Performance IQ and psychomotor speed, including switching. In the VLBW group, associations were found between lower spatial working memory and the presence of anxiety disorders, internalizing and attention problems, and autistic traits. Furthermore, lower Full scale IQ was associated with attention problems when adjusting for sex and parental socioeconomic status.ConclusionAdults born preterm with VLBW or born term SGA displayed neurocognitive difficulties. Spatial working memory was associated with difficulties with attention, anxiety, and social function of VLBW adults. The finding and its clinical applicability should be further explored. |
| first_indexed | 2024-04-10T22:16:31Z |
| format | Article |
| id | doaj.art-8cdd703ec2e34f98afbbe9ff1608059b |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-04-10T22:16:31Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-8cdd703ec2e34f98afbbe9ff1608059b2023-01-18T07:53:28ZengFrontiers Media S.A.Frontiers in Psychology1664-10782023-01-011310.3389/fpsyg.2022.10782321078232Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at termSiri Weider0Astrid M. W. Lærum1Astrid M. W. Lærum2Kari Anne I. Evensen3Kari Anne I. Evensen4Kari Anne I. Evensen5Kari Anne I. Evensen6Solveig Klæbo Reitan7Solveig Klæbo Reitan8Stian Lydersen9Ann Mari Brubakk10Jon Skranes11Jon Skranes12Marit S. Indredavik13Department of Psychology, Faculty of Social and Educational Sciences, Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayChildren’s Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayChildren’s Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayUnit for Physiotherapy Services, Trondheim Municipality, Trondheim, NorwayDepartment of Physiotherapy, Oslo Metropolitan University, Oslo, NorwayDepartment of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Psychiatry, Division of Mental Health Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayDepartment of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayDepartment of Pediatrics, Sørlandet Hospital, Arendal, NorwayDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, NorwayObjectivesTo assess neurocognitive function in adults born with low birthweight compared with controls and to explore associations between neurocognitive function and psychopathology in these groups.MethodsIn this prospective cohort study, one group born preterm with very low birthweight (VLBW: birthweight <1,500 g, n = 53), one group born small for gestational age at term (SGA: birthweight <10th percentile, n = 63) and one term-born control group (birthweight ≥10th percentile, n = 81) were assessed with neurocognitive tests, diagnostic interviews, and self-report questionnaires at 26 years of age.ResultsThe VLBW group scored significantly below the control group on several neurocognitive measures, including IQ measures, psychomotor speed, verbal fluency, aspects of visual learning and memory, attention, social cognition, working memory and fine motor speed. The SGA group consistently scored at an intermediate level between the VLBW and the control group and had significantly lower scores than controls on Performance IQ and psychomotor speed, including switching. In the VLBW group, associations were found between lower spatial working memory and the presence of anxiety disorders, internalizing and attention problems, and autistic traits. Furthermore, lower Full scale IQ was associated with attention problems when adjusting for sex and parental socioeconomic status.ConclusionAdults born preterm with VLBW or born term SGA displayed neurocognitive difficulties. Spatial working memory was associated with difficulties with attention, anxiety, and social function of VLBW adults. The finding and its clinical applicability should be further explored.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.1078232/fullexecutive functionmental healthpsychiatric symptoms and disorderspreterm birthworking memoryintelligence |
| spellingShingle | Siri Weider Astrid M. W. Lærum Astrid M. W. Lærum Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Kari Anne I. Evensen Solveig Klæbo Reitan Solveig Klæbo Reitan Stian Lydersen Ann Mari Brubakk Jon Skranes Jon Skranes Marit S. Indredavik Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term Frontiers in Psychology executive function mental health psychiatric symptoms and disorders preterm birth working memory intelligence |
| title | Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| title_full | Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| title_fullStr | Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| title_full_unstemmed | Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| title_short | Neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| title_sort | neurocognitive function and associations with mental health in adults born preterm with very low birthweight or small for gestational age at term |
| topic | executive function mental health psychiatric symptoms and disorders preterm birth working memory intelligence |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.1078232/full |
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