Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging
The fluorescent carbon dots (CDs) have found their extensive applications in sensing, bioimaging, and photoelectronic devices. In general terms, the synthesis of CDs is straight-forward, though their subsequent purification can be laborious. Therefore, there is a need for easier ways to generate sol...
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| Format: | Article |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1006389/full |
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| author | Xiaoyun Qin Xiaoyun Qin Cuicui Fu Jin Zhang Wenlong Shao Xiaomei Qin Yanghai Gui Lan Wang Huishi Guo Fenghua Chen Liying Jiang Gang Wu Gang Wu Floris J. Bikker Dan Luo |
| author_facet | Xiaoyun Qin Xiaoyun Qin Cuicui Fu Jin Zhang Wenlong Shao Xiaomei Qin Yanghai Gui Lan Wang Huishi Guo Fenghua Chen Liying Jiang Gang Wu Gang Wu Floris J. Bikker Dan Luo |
| author_sort | Xiaoyun Qin |
| collection | DOAJ |
| description | The fluorescent carbon dots (CDs) have found their extensive applications in sensing, bioimaging, and photoelectronic devices. In general terms, the synthesis of CDs is straight-forward, though their subsequent purification can be laborious. Therefore, there is a need for easier ways to generate solid CDs with a high conversion yield. Herein, we used collagen waste as a carbon source in producing solid CDs through a calcination procedure without additional chemical decomposition treatment of the raw material. Considering a mass of acid has destroyed the original protein macromolecules into the assembled structure with amino acids and peptide chains in the commercial extraction procedure of collagen product. The residual tissues were assembled with weak intermolecular interactions, which would easily undergo dehydration, polymerization, and carbonization during the heat treatment to produce solid CDs directly. The calcination parameters were surveyed to give the highest conversion yield at 78%, which occurred at 300°C for 2 h. N and S atomic doping CDs (N-CDs and S-CDs) were synthesized at a similar process except for immersion of the collagen waste in sulfuric acid or nitric acid in advance. Further experiments suggested the prepared CDs can serve as an excellent sensor platform for Fe3+ in an acid medium with high anti-interference. The cytotoxicity assays confirmed the biosafety and biocompatibility of the CDs, suggesting potential applications in bioimaging. This work provides a new avenue for preparing solid CDs with high conversion yield. |
| first_indexed | 2024-04-12T22:59:22Z |
| format | Article |
| id | doaj.art-8ce1509df32b475ba97ceff137e2d557 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-12T22:59:22Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-8ce1509df32b475ba97ceff137e2d5572022-12-22T03:13:06ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-09-011010.3389/fchem.2022.10063891006389Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imagingXiaoyun Qin0Xiaoyun Qin1Cuicui Fu2Jin Zhang3Wenlong Shao4Xiaomei Qin5Yanghai Gui6Lan Wang7Huishi Guo8Fenghua Chen9Liying Jiang10Gang Wu11Gang Wu12Floris J. Bikker13Dan Luo14School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaCAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, ChinaDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam (UvA) and Vrije Universiteit Amsterdam (VU), Amsterdam, NetherlandsSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaSchool of Electrical and Information Engineering, Zhengzhou University of Light Industry, Zhengzhou, ChinaDepartment of Oral and Maxillofacial Surgery/Pathology, Amsterdam UMC and Academic Center for Dentistry Amsterdam (ACTA), Amsterdam Movement Science, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsDepartment of Oral Cell Biology, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, NetherlandsDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam (UvA) and Vrije Universiteit Amsterdam (VU), Amsterdam, NetherlandsCAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, ChinaThe fluorescent carbon dots (CDs) have found their extensive applications in sensing, bioimaging, and photoelectronic devices. In general terms, the synthesis of CDs is straight-forward, though their subsequent purification can be laborious. Therefore, there is a need for easier ways to generate solid CDs with a high conversion yield. Herein, we used collagen waste as a carbon source in producing solid CDs through a calcination procedure without additional chemical decomposition treatment of the raw material. Considering a mass of acid has destroyed the original protein macromolecules into the assembled structure with amino acids and peptide chains in the commercial extraction procedure of collagen product. The residual tissues were assembled with weak intermolecular interactions, which would easily undergo dehydration, polymerization, and carbonization during the heat treatment to produce solid CDs directly. The calcination parameters were surveyed to give the highest conversion yield at 78%, which occurred at 300°C for 2 h. N and S atomic doping CDs (N-CDs and S-CDs) were synthesized at a similar process except for immersion of the collagen waste in sulfuric acid or nitric acid in advance. Further experiments suggested the prepared CDs can serve as an excellent sensor platform for Fe3+ in an acid medium with high anti-interference. The cytotoxicity assays confirmed the biosafety and biocompatibility of the CDs, suggesting potential applications in bioimaging. This work provides a new avenue for preparing solid CDs with high conversion yield.https://www.frontiersin.org/articles/10.3389/fchem.2022.1006389/fullcarbon dotsbiomassconversion yieldsensingiron ionsbioimaging |
| spellingShingle | Xiaoyun Qin Xiaoyun Qin Cuicui Fu Jin Zhang Wenlong Shao Xiaomei Qin Yanghai Gui Lan Wang Huishi Guo Fenghua Chen Liying Jiang Gang Wu Gang Wu Floris J. Bikker Dan Luo Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging Frontiers in Chemistry carbon dots biomass conversion yield sensing iron ions bioimaging |
| title | Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| title_full | Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| title_fullStr | Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| title_full_unstemmed | Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| title_short | Direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| title_sort | direct preparation of solid carbon dots by pyrolysis of collagen waste and their applications in fluorescent sensing and imaging |
| topic | carbon dots biomass conversion yield sensing iron ions bioimaging |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.1006389/full |
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