Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report

Objective: To determine the incidence of deep vein thrombosis (DVT) in patients undergoing spinal surgeries receiving prophylactic doses of Deltaparin in a single center in central Iran.Method: This cross-sectional study was conducted in Shariatee hospital of Isfahan during a 12-month period. We inc...

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Main Authors: Alireza Farid Moayer, Navideh Mohebali, Ali Razmkon
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2016-01-01
Series:Bulletin of Emergency and Trauma
Subjects:
Online Access:http://beat.sums.ac.ir/article_44307_4882586dc443c0877b8fa9530e0ff838.pdf
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author Alireza Farid Moayer
Navideh Mohebali
Ali Razmkon
author_facet Alireza Farid Moayer
Navideh Mohebali
Ali Razmkon
author_sort Alireza Farid Moayer
collection DOAJ
description Objective: To determine the incidence of deep vein thrombosis (DVT) in patients undergoing spinal surgeries receiving prophylactic doses of Deltaparin in a single center in central Iran.Method: This cross-sectional study was conducted in Shariatee hospital of Isfahan during a 12-month period. We included all the patients undergoing elective spinal surgeries in our center during the study period who received prophylactic dosages of subcutaneous Dalteparin (5000 unit daily) the first postoperative day. Those with absolute contraindications of anticoagulation therapy were not included in the study. Patients were followed for 3 months clinically and the incidence of DVT was recorded. DVT was suspected clinically and was confirmed by color Doppler sonography.Results: Overall we included 120 patients with mean age of 44.8 ± 12.6 years among whom there were 54 (45%) men and 66 (55%) women. Lumbar discectomy (32.9%) and laminectomy (20.2%) were the most common performed procedures. DVT was detected in 1 (0.83%) patient in postoperative period. None of the patients developed pulmonary embolism and none hemorrhagic adverse event was recorded. The patient was treated with therapeutic unfractionated heparin and was discharged with warfarin. Conclusion: Our results shows the efficacy of LMWH (Dalteparin) in reducing the incidence of DVT to 0.83%. These results also show the safety of Dalteparin in spine surgery because of lack of bleeding complication.
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spelling doaj.art-8ce310c2cf9c4d2589fafc8343428e412022-12-21T19:09:52ZengShiraz University of Medical SciencesBulletin of Emergency and Trauma2322-25222322-39602016-01-014Issue 1384244307Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center ReportAlireza Farid MoayerNavideh MohebaliAli RazmkonObjective: To determine the incidence of deep vein thrombosis (DVT) in patients undergoing spinal surgeries receiving prophylactic doses of Deltaparin in a single center in central Iran.Method: This cross-sectional study was conducted in Shariatee hospital of Isfahan during a 12-month period. We included all the patients undergoing elective spinal surgeries in our center during the study period who received prophylactic dosages of subcutaneous Dalteparin (5000 unit daily) the first postoperative day. Those with absolute contraindications of anticoagulation therapy were not included in the study. Patients were followed for 3 months clinically and the incidence of DVT was recorded. DVT was suspected clinically and was confirmed by color Doppler sonography.Results: Overall we included 120 patients with mean age of 44.8 ± 12.6 years among whom there were 54 (45%) men and 66 (55%) women. Lumbar discectomy (32.9%) and laminectomy (20.2%) were the most common performed procedures. DVT was detected in 1 (0.83%) patient in postoperative period. None of the patients developed pulmonary embolism and none hemorrhagic adverse event was recorded. The patient was treated with therapeutic unfractionated heparin and was discharged with warfarin. Conclusion: Our results shows the efficacy of LMWH (Dalteparin) in reducing the incidence of DVT to 0.83%. These results also show the safety of Dalteparin in spine surgery because of lack of bleeding complication.http://beat.sums.ac.ir/article_44307_4882586dc443c0877b8fa9530e0ff838.pdfDeep Vein ThrombosisSpinal surgeryDalteparinLow molecular weight heparin (LMWH)Pulmonary thromboembolism (PTE)
spellingShingle Alireza Farid Moayer
Navideh Mohebali
Ali Razmkon
Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
Bulletin of Emergency and Trauma
Deep Vein Thrombosis
Spinal surgery
Dalteparin
Low molecular weight heparin (LMWH)
Pulmonary thromboembolism (PTE)
title Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
title_full Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
title_fullStr Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
title_full_unstemmed Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
title_short Incidence of Deep Vein Thrombosis in Patients Undergoing Degenerative Spine Surgery on Prophylactic Dalteparin; A Single Center Report
title_sort incidence of deep vein thrombosis in patients undergoing degenerative spine surgery on prophylactic dalteparin a single center report
topic Deep Vein Thrombosis
Spinal surgery
Dalteparin
Low molecular weight heparin (LMWH)
Pulmonary thromboembolism (PTE)
url http://beat.sums.ac.ir/article_44307_4882586dc443c0877b8fa9530e0ff838.pdf
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