SBML Level 3 package: Qualitative Models, Version 1, Release 1

Quantitative methods for modelling biological networks require an in-depth knowledge of the biochemical reactions and their stoichiometric and kinetic parameters. In many practical cases, this knowledge is missing. This has led to the development of several qualitative modelling methods using inform...

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Main Authors: Chaouiya Claudine, Keating Sarah M., Berenguier Duncan, Naldi Aurélien, Thieffry Denis, Iersel Martijn P. van, Le Novère Nicolas, Helikar Tomáš
Format: Article
Language:English
Published: De Gruyter 2015-06-01
Series:Journal of Integrative Bioinformatics
Online Access:https://doi.org/10.1515/jib-2015-270
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author Chaouiya Claudine
Keating Sarah M.
Berenguier Duncan
Naldi Aurélien
Thieffry Denis
Iersel Martijn P. van
Le Novère Nicolas
Helikar Tomáš
author_facet Chaouiya Claudine
Keating Sarah M.
Berenguier Duncan
Naldi Aurélien
Thieffry Denis
Iersel Martijn P. van
Le Novère Nicolas
Helikar Tomáš
author_sort Chaouiya Claudine
collection DOAJ
description Quantitative methods for modelling biological networks require an in-depth knowledge of the biochemical reactions and their stoichiometric and kinetic parameters. In many practical cases, this knowledge is missing. This has led to the development of several qualitative modelling methods using information such as, for example, gene expression data coming from functional genomic experiments. The SBML Level 3 Version 1 Core specification does not provide a mechanism for explicitly encoding qualitative models, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactical constructs.
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spelling doaj.art-8ce6e81f6b254b5eab23c6a516d9ac942022-12-21T22:33:42ZengDe GruyterJournal of Integrative Bioinformatics1613-45162015-06-0112269173010.1515/jib-2015-270jib-2015-270SBML Level 3 package: Qualitative Models, Version 1, Release 1Chaouiya Claudine0Keating Sarah M.1Berenguier Duncan2Naldi Aurélien3Thieffry Denis4Iersel Martijn P. van5Le Novère Nicolas6Helikar Tomáš7IGC Rua da Quinta Grande 6, P-2780-156, Oeiras, PortugalEuropean Bioinformatics Institute EMBL-EBI, Cambridgeshire, United Kingdom of Great Britain and Northern IrelandTAGC INSERM U928, 13288Marseille, FranceCenter for Integrative Genomics, CH-1015Lausanne, SwitzerlandIBENS, 75005Paris, FranceEuropean Bioinformatics Institute EMBL-EBI, Cambridgeshire, United Kingdom of Great Britain and Northern IrelandBabraham Institute, Cambridgeshire, United Kingdom of Great Britain and Northern IrelandDepartment of Mathematics, University of Nebraska Medical Center, Omaha, United States of AmericaQuantitative methods for modelling biological networks require an in-depth knowledge of the biochemical reactions and their stoichiometric and kinetic parameters. In many practical cases, this knowledge is missing. This has led to the development of several qualitative modelling methods using information such as, for example, gene expression data coming from functional genomic experiments. The SBML Level 3 Version 1 Core specification does not provide a mechanism for explicitly encoding qualitative models, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactical constructs.https://doi.org/10.1515/jib-2015-270
spellingShingle Chaouiya Claudine
Keating Sarah M.
Berenguier Duncan
Naldi Aurélien
Thieffry Denis
Iersel Martijn P. van
Le Novère Nicolas
Helikar Tomáš
SBML Level 3 package: Qualitative Models, Version 1, Release 1
Journal of Integrative Bioinformatics
title SBML Level 3 package: Qualitative Models, Version 1, Release 1
title_full SBML Level 3 package: Qualitative Models, Version 1, Release 1
title_fullStr SBML Level 3 package: Qualitative Models, Version 1, Release 1
title_full_unstemmed SBML Level 3 package: Qualitative Models, Version 1, Release 1
title_short SBML Level 3 package: Qualitative Models, Version 1, Release 1
title_sort sbml level 3 package qualitative models version 1 release 1
url https://doi.org/10.1515/jib-2015-270
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