The Antifungal Peptide MCh-AMP1 Derived From Matricaria chamomilla Inhibits Candida albicans Growth via Inducing ROS Generation and Altering Fungal Cell Membrane Permeability

The Antifungal Peptide MCh-AMP1 Derived From Matricaria chamomilla Inhibits Candida albicans Growth via Inducing ROS Generation and Altering Fungal Cell Membrane Permeability

The rise of antifungal drug resistance in Candida species responsible for life threatening candidiasis is considered as an increasing challenge for the public health. MCh-AMP1 has previously been reported as a natural peptide from Matricaria chamomilla L. flowers with broad-spectrum antifungal activ...

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Bibliographic Details
Main Authors: Sima Sadat Seyedjavadi, Soghra Khani, Ali Eslamifar, Soheila Ajdary, Mehdi Goudarzi, Raheleh Halabian, Reza Akbari, Hadi Zare-Zardini, Abbas Ali Imani Fooladi, Jafar Amani, Mehdi Razzaghi-Abyaneh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
antifungal peptides
peptide synthesis
Candida albicans
antifungal activity
time killing assay
electron microscopy
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.03150/full

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