Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes

Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes

An asymmetric annulation reaction of γ-butenolides and cyclic 1-azadienes containing a 1,2-benzoisothiazole-1,1-dioxide motif has been studied, proceeding in a tandem Michael addition-aza-Michael addition sequence. Endo-type cycloadducts bearing fused tetracyclic skeletons were isolated in fair yiel...

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Bibliographic Details
Main Authors:	Chao Li, Kun Jiang, Ying-Chun Chen
Format:	Article
Language:	English
Published:	MDPI AG 2015-07-01
Series:	Molecules
Subjects:	asymmetric organocatalysis Brønsted base cinchona alkaloids butenolides 1-azadienes diastereodivergence
Online Access:	http://www.mdpi.com/1420-3049/20/8/13642

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