Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer’s disease treatment

Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer’s disease treatment

Butyrylcholinesterase (BChE) performs a significant function in Alzheimer’s disease progression. Experimental studies have shown that the function of BChE in the attenuation of cholinergic neurotransmission is essentially altered in brains of advanced AD patients. Here, using the complimentary metho...

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Bibliographic Details
Main Authors: Sani Muhammad Uzairu, Yahaya Tijani, Madu Adamu Gadaka, Babagana Modu, Miriam Watafua, Hadiza Ali Ahmad, Umar Abdullahi Zakariya, Aminu Ibrahim, Aliyu Daja, Hassan Zanna, Abdullahi Balarabe Sallau
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Heliyon
Subjects:
Butyrylcholinesterase
Methylrosmarinate
Enzyme inhibition
Enzyme kinetics
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022019016

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