HTQC: a fast quality control toolkit for Illumina sequencing data

<p>Abstract</p> <p>Background</p> <p>Illumina sequencing platform is widely used in genome research. Sequence reads quality assessment and control are needed for downstream analysis. However, software that provides efficient quality assessment and versatile filtration m...

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Main Authors: Yang Xi, Liu Di, Liu Fei, Wu Jun, Zou Jing, Xiao Xue, Zhao Fangqing, Zhu Baoli
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/14/33
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author Yang Xi
Liu Di
Liu Fei
Wu Jun
Zou Jing
Xiao Xue
Zhao Fangqing
Zhu Baoli
author_facet Yang Xi
Liu Di
Liu Fei
Wu Jun
Zou Jing
Xiao Xue
Zhao Fangqing
Zhu Baoli
author_sort Yang Xi
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Illumina sequencing platform is widely used in genome research. Sequence reads quality assessment and control are needed for downstream analysis. However, software that provides efficient quality assessment and versatile filtration methods is still lacking.</p> <p>Results</p> <p>We have developed a toolkit named HTQC – abbreviation of High-Throughput Quality Control – for sequence reads quality control, which consists of six programs for reads quality assessment, reads filtration and generation of graphic reports.</p> <p>Conclusions</p> <p>The HTQC toolkit can generate reads quality assessment faster than existing tools, providing guidance for reads filtration utilities that allow users to choose different strategies to remove low quality reads.</p>
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spelling doaj.art-8ced4722386745f68daf4f95d12326f72022-12-21T21:03:22ZengBMCBMC Bioinformatics1471-21052013-01-011413310.1186/1471-2105-14-33HTQC: a fast quality control toolkit for Illumina sequencing dataYang XiLiu DiLiu FeiWu JunZou JingXiao XueZhao FangqingZhu Baoli<p>Abstract</p> <p>Background</p> <p>Illumina sequencing platform is widely used in genome research. Sequence reads quality assessment and control are needed for downstream analysis. However, software that provides efficient quality assessment and versatile filtration methods is still lacking.</p> <p>Results</p> <p>We have developed a toolkit named HTQC – abbreviation of High-Throughput Quality Control – for sequence reads quality control, which consists of six programs for reads quality assessment, reads filtration and generation of graphic reports.</p> <p>Conclusions</p> <p>The HTQC toolkit can generate reads quality assessment faster than existing tools, providing guidance for reads filtration utilities that allow users to choose different strategies to remove low quality reads.</p>http://www.biomedcentral.com/1471-2105/14/33
spellingShingle Yang Xi
Liu Di
Liu Fei
Wu Jun
Zou Jing
Xiao Xue
Zhao Fangqing
Zhu Baoli
HTQC: a fast quality control toolkit for Illumina sequencing data
BMC Bioinformatics
title HTQC: a fast quality control toolkit for Illumina sequencing data
title_full HTQC: a fast quality control toolkit for Illumina sequencing data
title_fullStr HTQC: a fast quality control toolkit for Illumina sequencing data
title_full_unstemmed HTQC: a fast quality control toolkit for Illumina sequencing data
title_short HTQC: a fast quality control toolkit for Illumina sequencing data
title_sort htqc a fast quality control toolkit for illumina sequencing data
url http://www.biomedcentral.com/1471-2105/14/33
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