Choriocarcinoma in Cesarean Scar Site: A Case Report

Background & aim: Cesarean scar pregnancy is an ectopic pregnancy implanted in the myometrium at the site of a previous cesarean section scar and is the rarest kind of ectopic pregnancy. The present study present a case of choriocarcinoma (CC) in the cesarean scar. The clinical course, findings,...

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Main Authors: Helena Azimi, Laya Shirinzadeh, Amir Hosein Jafarian, Behroz Davachi, Somayeh Bolandi, Sepideh Hoseini, Tahereh Zavvari, Zohreh Yousefi, Fatemeh Shirzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-04-01
Series:Journal of Midwifery & Reproductive Health
Subjects:
Online Access:https://jmrh.mums.ac.ir/article_17552_9c0c7bf63ff54a2d1f22891e3e2f716b.pdf
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author Helena Azimi
Laya Shirinzadeh
Amir Hosein Jafarian
Behroz Davachi
Somayeh Bolandi
Sepideh Hoseini
Tahereh Zavvari
Zohreh Yousefi
Fatemeh Shirzadeh
author_facet Helena Azimi
Laya Shirinzadeh
Amir Hosein Jafarian
Behroz Davachi
Somayeh Bolandi
Sepideh Hoseini
Tahereh Zavvari
Zohreh Yousefi
Fatemeh Shirzadeh
author_sort Helena Azimi
collection DOAJ
description Background & aim: Cesarean scar pregnancy is an ectopic pregnancy implanted in the myometrium at the site of a previous cesarean section scar and is the rarest kind of ectopic pregnancy. The present study present a case of choriocarcinoma (CC) in the cesarean scar. The clinical course, findings, and treatment plan are discussed. Case report: A 41-years old multi-gravid woman with a history of one previous cesarean section and three subsequent abortions was admitted to the hospital. She suffered from an unknown abnormal vaginal bleeding for two months. Β-HCG titer was 1,000 IU/L and the report of sonography showed no gestational sac. Accordingly, the patient was diagnosed with ectopic pregnancy in the cesarean scar site and, therefore, weekly usage of methotrexate was prescribed for her. Since she did not respond to the treatment, she was referred to our department in the Faculty of Medicine. The evaluation showed mass invasion through the entire uterine wall. The uterus preservation was not possible, therefore, total hysterectomy was performed. The pathology report confirmed CC in the cesarean scar. Conclusion: Based on previous studies, as the number of cesarean sections increases, the possibility of complications rises, as well.  Cesarean scars implantation of CC is one of the rare complications of caesarean section. The probability of a gestational trophoblastic disease should be considered in any woman during her pregnancy. Early detection and proper management of the complications can result in a decrease in morbidity and mortality.
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spelling doaj.art-8ceed5dd13374cfd9f74c8f15a989bc82022-12-22T04:17:03ZengMashhad University of Medical SciencesJournal of Midwifery & Reproductive Health2345-47922345-47922021-04-01922767277210.22038/jmrh.2020.43382.151417552Choriocarcinoma in Cesarean Scar Site: A Case ReportHelena Azimi0Laya Shirinzadeh1Amir Hosein Jafarian2Behroz Davachi3Somayeh Bolandi4Sepideh Hoseini5Tahereh Zavvari6Zohreh Yousefi7Fatemeh Shirzadeh8Assistant professor, Fellowship of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranGynecologist, Fellowship of Gynecologic Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranAssociate Professor, Department of Radiology, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, IranAssociate Professor, Department of Radiology, Faculty of Medicine, , Mashhad University of Medical Sciences, Mashhad, IranGynecologist, Fellowship of Gynecologic Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranResident, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranBCs in Midwifery, Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, IranProfessor, Department of Obstetrics and Gynecology, Fellowship of Gynecologic Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranBCs in Nursing, Department of Nursing , School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, IranBackground & aim: Cesarean scar pregnancy is an ectopic pregnancy implanted in the myometrium at the site of a previous cesarean section scar and is the rarest kind of ectopic pregnancy. The present study present a case of choriocarcinoma (CC) in the cesarean scar. The clinical course, findings, and treatment plan are discussed. Case report: A 41-years old multi-gravid woman with a history of one previous cesarean section and three subsequent abortions was admitted to the hospital. She suffered from an unknown abnormal vaginal bleeding for two months. Β-HCG titer was 1,000 IU/L and the report of sonography showed no gestational sac. Accordingly, the patient was diagnosed with ectopic pregnancy in the cesarean scar site and, therefore, weekly usage of methotrexate was prescribed for her. Since she did not respond to the treatment, she was referred to our department in the Faculty of Medicine. The evaluation showed mass invasion through the entire uterine wall. The uterus preservation was not possible, therefore, total hysterectomy was performed. The pathology report confirmed CC in the cesarean scar. Conclusion: Based on previous studies, as the number of cesarean sections increases, the possibility of complications rises, as well.  Cesarean scars implantation of CC is one of the rare complications of caesarean section. The probability of a gestational trophoblastic disease should be considered in any woman during her pregnancy. Early detection and proper management of the complications can result in a decrease in morbidity and mortality.https://jmrh.mums.ac.ir/article_17552_9c0c7bf63ff54a2d1f22891e3e2f716b.pdfectopic pregnancycesarean scarchoriocarcinoma
spellingShingle Helena Azimi
Laya Shirinzadeh
Amir Hosein Jafarian
Behroz Davachi
Somayeh Bolandi
Sepideh Hoseini
Tahereh Zavvari
Zohreh Yousefi
Fatemeh Shirzadeh
Choriocarcinoma in Cesarean Scar Site: A Case Report
Journal of Midwifery & Reproductive Health
ectopic pregnancy
cesarean scar
choriocarcinoma
title Choriocarcinoma in Cesarean Scar Site: A Case Report
title_full Choriocarcinoma in Cesarean Scar Site: A Case Report
title_fullStr Choriocarcinoma in Cesarean Scar Site: A Case Report
title_full_unstemmed Choriocarcinoma in Cesarean Scar Site: A Case Report
title_short Choriocarcinoma in Cesarean Scar Site: A Case Report
title_sort choriocarcinoma in cesarean scar site a case report
topic ectopic pregnancy
cesarean scar
choriocarcinoma
url https://jmrh.mums.ac.ir/article_17552_9c0c7bf63ff54a2d1f22891e3e2f716b.pdf
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AT layashirinzadeh choriocarcinomaincesareanscarsiteacasereport
AT amirhoseinjafarian choriocarcinomaincesareanscarsiteacasereport
AT behrozdavachi choriocarcinomaincesareanscarsiteacasereport
AT somayehbolandi choriocarcinomaincesareanscarsiteacasereport
AT sepidehhoseini choriocarcinomaincesareanscarsiteacasereport
AT taherehzavvari choriocarcinomaincesareanscarsiteacasereport
AT zohrehyousefi choriocarcinomaincesareanscarsiteacasereport
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