Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer.

Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer.

Selective targeting of cancer-associated fibroblasts (CAFs) has been proposed to synergize with immune-checkpoint inhibitors. While the roles of CAFs in cancer development are well described, their immune-regulatory properties remain incompletely understood. This study investigates correlations betw...

Full description

Bibliographic Details
Main Authors: Thomas Karsten Kilvaer, Mehrdad Rakaee, Turid Hellevik, Arne Østman, Carina Strell, Roy M Bremnes, Lill-Tove Busund, Tom Dønnem, Inigo Martinez-Zubiaurre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5802915?pdf=render

Similar Items

Similar Items