Post Partum Depression and Thyroid Function
Objective: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2011-09-01
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| Series: | Iranian Journal of Psychiatry |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/upload_files/pdf/19376.pdf |
| _version_ | 1818146441214820352 |
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| author | Farahnaz Keshavarzi MD Katayoun Yazdchi MD Mehrali Rahimi MD Mansour Rezaei MD Vahid Farnia MD Omran Davarinejad MD Nasrin Abdoli Msc Mahmood Jalili MD |
| author_facet | Farahnaz Keshavarzi MD Katayoun Yazdchi MD Mehrali Rahimi MD Mansour Rezaei MD Vahid Farnia MD Omran Davarinejad MD Nasrin Abdoli Msc Mahmood Jalili MD |
| author_sort | Farahnaz Keshavarzi MD |
| collection | DOAJ |
| description | Objective: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression compared to a control group.Methods: In this case-control study, subjects were selected from Obstetrics & Gynecology and Psychiatric clinics of Kermanshah University of Medical Sciences. Forty eight patients suffering from postpartum depression according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition totally revised (DSM-IV-TR), and 65 normal controls underwent diagnostic evaluation by one trained psychiatrist using Structured Clinical Interview for DSM-IV-TR. Then, the demographic questionnaire and the Persian version of Edinburgh Postnatal Depression Scale (EPDS) were completed by the participants. Finally, their thyroid functions were assessed. Data analyses were done using the SPSS program 13.Results: No statistically significant differences were observed between thyroid function tests and postpartum depression. According to multiple regression analysis with stepwise method, subjects with lower serum TSH, T3RU, T3 levels, younger age and longer period after delivery tended to have higher EPDS scores (P-value=0.008). Conclusion:The present study reports that those women with postpartum depression had a no greater prevalence of thyroid dysfunction than the control subjects. It seems that thyroid dysfunction should be considered in women with postpartum depression individually, but the role of thyroid as an important cause of this condition is not yet established. This suggests that future studies should concentrate on this concept in postpartum depression. |
| first_indexed | 2024-12-11T12:19:24Z |
| format | Article |
| id | doaj.art-8cfa5f02308f44649ef2eda84eb6e85d |
| institution | Directory Open Access Journal |
| issn | 1735-4587 2008-2215 |
| language | English |
| last_indexed | 2024-12-11T12:19:24Z |
| publishDate | 2011-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Psychiatry |
| spelling | doaj.art-8cfa5f02308f44649ef2eda84eb6e85d2022-12-22T01:07:35ZengTehran University of Medical SciencesIranian Journal of Psychiatry1735-45872008-22152011-09-0163117120Post Partum Depression and Thyroid FunctionFarahnaz Keshavarzi MDKatayoun Yazdchi MDMehrali Rahimi MDMansour Rezaei MDVahid Farnia MDOmran Davarinejad MDNasrin Abdoli MscMahmood Jalili MDObjective: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression compared to a control group.Methods: In this case-control study, subjects were selected from Obstetrics & Gynecology and Psychiatric clinics of Kermanshah University of Medical Sciences. Forty eight patients suffering from postpartum depression according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition totally revised (DSM-IV-TR), and 65 normal controls underwent diagnostic evaluation by one trained psychiatrist using Structured Clinical Interview for DSM-IV-TR. Then, the demographic questionnaire and the Persian version of Edinburgh Postnatal Depression Scale (EPDS) were completed by the participants. Finally, their thyroid functions were assessed. Data analyses were done using the SPSS program 13.Results: No statistically significant differences were observed between thyroid function tests and postpartum depression. According to multiple regression analysis with stepwise method, subjects with lower serum TSH, T3RU, T3 levels, younger age and longer period after delivery tended to have higher EPDS scores (P-value=0.008). Conclusion:The present study reports that those women with postpartum depression had a no greater prevalence of thyroid dysfunction than the control subjects. It seems that thyroid dysfunction should be considered in women with postpartum depression individually, but the role of thyroid as an important cause of this condition is not yet established. This suggests that future studies should concentrate on this concept in postpartum depression.http://journals.tums.ac.ir/upload_files/pdf/19376.pdfPostpartum DepressionPostpartum PeriodThyroid Hormone |
| spellingShingle | Farahnaz Keshavarzi MD Katayoun Yazdchi MD Mehrali Rahimi MD Mansour Rezaei MD Vahid Farnia MD Omran Davarinejad MD Nasrin Abdoli Msc Mahmood Jalili MD Post Partum Depression and Thyroid Function Iranian Journal of Psychiatry Postpartum Depression Postpartum Period Thyroid Hormone |
| title | Post Partum Depression and Thyroid Function |
| title_full | Post Partum Depression and Thyroid Function |
| title_fullStr | Post Partum Depression and Thyroid Function |
| title_full_unstemmed | Post Partum Depression and Thyroid Function |
| title_short | Post Partum Depression and Thyroid Function |
| title_sort | post partum depression and thyroid function |
| topic | Postpartum Depression Postpartum Period Thyroid Hormone |
| url | http://journals.tums.ac.ir/upload_files/pdf/19376.pdf |
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