Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides

Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides

Human leukocyte antigen (HLA) alleles have a high degree of polymorphism, which determines their peptide-binding motifs and subsequent T-cell receptor recognition. The simplest way to understand the cross-presentation of peptides by different alleles is to classify these alleles into supertypes. A1...

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Bibliographic Details
Main Authors: Shiyan Zhu, Kefang Liu, Yan Chai, Yanan Wu, Dan Lu, Wenling Xiao, Hao Cheng, Yingze Zhao, Chunming Ding, Jianxin Lyu, Yongliang Lou, George F. Gao, William J. Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
HLA-A3
HLA superfamily
cross-presentation
influenza virus
human immunodeficiency virus (HIV)
Mycobacterium tuberculosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01709/full

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