Metastasis from small cell lung cancer to ovary: A case report
Small cell lung cancer (SCLC) rarely metastasizes to the ovary, and is difficult to diagnose given its overlapping clinical features and histological characteristics with primary ovarian cancer. Since therapies for SCLC and primary ovarian cancer differ, it is important to determine the original sit...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-09-01
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| Series: | Open Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/biol-2022-0684 |
| _version_ | 1797693219084959744 |
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| author | Zhao Benzheng Zhao Weixin Xia Yang Liu Jian Wang Yuan Song Tianjiao Tan Wenxi Zhao Shuhua |
| author_facet | Zhao Benzheng Zhao Weixin Xia Yang Liu Jian Wang Yuan Song Tianjiao Tan Wenxi Zhao Shuhua |
| author_sort | Zhao Benzheng |
| collection | DOAJ |
| description | Small cell lung cancer (SCLC) rarely metastasizes to the ovary, and is difficult to diagnose given its overlapping clinical features and histological characteristics with primary ovarian cancer. Since therapies for SCLC and primary ovarian cancer differ, it is important to determine the original site of ovarian lesions. This report describes the differential diagnosis of metastatic from primary ovarian cancer. A 46-year-old Chinese woman with a history of SCLC, confirmed by transbronchial lung biopsy in August 2018, presented with abdominal distension in December 2018. Ultrasound examination and whole abdomen computed tomography showed one mass in each ovary. A provisional diagnosis of ovarian tumor was given. A palliative total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed; and three postoperative courses of chemotherapies. The patient died from multiple organ failure in May 2019. Metastatic ovarian cancer from SCLC was determined based on characteristic histological and immunohistochemical staining. |
| first_indexed | 2024-03-12T02:40:24Z |
| format | Article |
| id | doaj.art-8d01e8d911c647f59be7a94e5f1c5249 |
| institution | Directory Open Access Journal |
| issn | 2391-5412 |
| language | English |
| last_indexed | 2024-03-12T02:40:24Z |
| publishDate | 2023-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj.art-8d01e8d911c647f59be7a94e5f1c52492023-09-04T07:09:08ZengDe GruyterOpen Life Sciences2391-54122023-09-011811091310.1515/biol-2022-0684Metastasis from small cell lung cancer to ovary: A case reportZhao Benzheng0Zhao Weixin1Xia Yang2Liu Jian3Wang Yuan4Song Tianjiao5Tan Wenxi6Zhao Shuhua7Department of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun130041, ChinaDepartment of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun130041, ChinaDepartment of Pathology, Second Hospital of Jilin University, Changchun130041, ChinaDepartment of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun130041, ChinaSchool of Nursing, Jilin University, Changchun130021, ChinaSchool of Nursing, Jilin University, Changchun130021, ChinaDepartment of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun130041, ChinaDepartment of Obstetrics and Gynecology, Second Hospital of Jilin University, Changchun130041, ChinaSmall cell lung cancer (SCLC) rarely metastasizes to the ovary, and is difficult to diagnose given its overlapping clinical features and histological characteristics with primary ovarian cancer. Since therapies for SCLC and primary ovarian cancer differ, it is important to determine the original site of ovarian lesions. This report describes the differential diagnosis of metastatic from primary ovarian cancer. A 46-year-old Chinese woman with a history of SCLC, confirmed by transbronchial lung biopsy in August 2018, presented with abdominal distension in December 2018. Ultrasound examination and whole abdomen computed tomography showed one mass in each ovary. A provisional diagnosis of ovarian tumor was given. A palliative total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed; and three postoperative courses of chemotherapies. The patient died from multiple organ failure in May 2019. Metastatic ovarian cancer from SCLC was determined based on characteristic histological and immunohistochemical staining.https://doi.org/10.1515/biol-2022-0684small cell cancermetastatic ovarian tumorhypercalcemic typepulmonary typecase report |
| spellingShingle | Zhao Benzheng Zhao Weixin Xia Yang Liu Jian Wang Yuan Song Tianjiao Tan Wenxi Zhao Shuhua Metastasis from small cell lung cancer to ovary: A case report Open Life Sciences small cell cancer metastatic ovarian tumor hypercalcemic type pulmonary type case report |
| title | Metastasis from small cell lung cancer to ovary: A case report |
| title_full | Metastasis from small cell lung cancer to ovary: A case report |
| title_fullStr | Metastasis from small cell lung cancer to ovary: A case report |
| title_full_unstemmed | Metastasis from small cell lung cancer to ovary: A case report |
| title_short | Metastasis from small cell lung cancer to ovary: A case report |
| title_sort | metastasis from small cell lung cancer to ovary a case report |
| topic | small cell cancer metastatic ovarian tumor hypercalcemic type pulmonary type case report |
| url | https://doi.org/10.1515/biol-2022-0684 |
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