Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature
Many qualitative and quantitative Magnetic Resonance Imaging (MRI) techniques have been applied to evaluate muscle fat degeneration in Duchenne muscular dystrophy (DMD) subjects, but only few studies have focused on the upper limbs. We reviewed the literature in order to evaluate the association bet...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/3/440 |
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| author | Lara Cristiano Claudia Brogna Giorgio Tasca Tommaso Verdolotti Marika Pane Eugenio Mercuri |
| author_facet | Lara Cristiano Claudia Brogna Giorgio Tasca Tommaso Verdolotti Marika Pane Eugenio Mercuri |
| author_sort | Lara Cristiano |
| collection | DOAJ |
| description | Many qualitative and quantitative Magnetic Resonance Imaging (MRI) techniques have been applied to evaluate muscle fat degeneration in Duchenne muscular dystrophy (DMD) subjects, but only few studies have focused on the upper limbs. We reviewed the literature in order to evaluate the association between muscle MRI findings and motor function levels in the upper limbs of DMD patients. Ten studies with upper limb muscle MRI data were available. Four explored all upper limb segments, while six explored only the forearm. Functional assessments were performed in nine of the ten studies. All of the studies showed a significant correlation between muscle MRI changes and motor function levels in both ambulant and non-ambulant DMD patients. |
| first_indexed | 2024-03-09T13:23:30Z |
| format | Article |
| id | doaj.art-8d049c8da75b4f9f835c8d5fc7e7db21 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T13:23:30Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-8d049c8da75b4f9f835c8d5fc7e7db212023-11-30T21:27:03ZengMDPI AGMedicina1010-660X1648-91442022-03-0158344010.3390/medicina58030440Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the LiteratureLara Cristiano0Claudia Brogna1Giorgio Tasca2Tommaso Verdolotti3Marika Pane4Eugenio Mercuri5Pediatric Neurology Unit, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyPediatric Neurology Unit, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyUnità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyInstitute of Radiology, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyPediatric Neurology Unit, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyPediatric Neurology Unit, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, 00168 Rome, ItalyMany qualitative and quantitative Magnetic Resonance Imaging (MRI) techniques have been applied to evaluate muscle fat degeneration in Duchenne muscular dystrophy (DMD) subjects, but only few studies have focused on the upper limbs. We reviewed the literature in order to evaluate the association between muscle MRI findings and motor function levels in the upper limbs of DMD patients. Ten studies with upper limb muscle MRI data were available. Four explored all upper limb segments, while six explored only the forearm. Functional assessments were performed in nine of the ten studies. All of the studies showed a significant correlation between muscle MRI changes and motor function levels in both ambulant and non-ambulant DMD patients.https://www.mdpi.com/1648-9144/58/3/440muscle MRIPULDMDupper limbs |
| spellingShingle | Lara Cristiano Claudia Brogna Giorgio Tasca Tommaso Verdolotti Marika Pane Eugenio Mercuri Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature Medicina muscle MRI PUL DMD upper limbs |
| title | Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature |
| title_full | Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature |
| title_fullStr | Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature |
| title_full_unstemmed | Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature |
| title_short | Muscle-MRI and Functional Levels for the Evaluation of Upper Limbs in Duchenne Muscular Dystrophy: A Critical Review of the Literature |
| title_sort | muscle mri and functional levels for the evaluation of upper limbs in duchenne muscular dystrophy a critical review of the literature |
| topic | muscle MRI PUL DMD upper limbs |
| url | https://www.mdpi.com/1648-9144/58/3/440 |
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