Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model

Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model

Cartilage has poor regenerative capacity and thus damage to the joint surfaces presents a major clinical challenge. Recent research has focussed on the development of tissue-engineered and cell-based approaches for the treatment of cartilage and osteochondral injuries, with current clinically availa...

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Bibliographic Details
Main Authors: Tanya J. Levingstone, Eamon J. Sheehy, Conor J. Moran, Gráinne M. Cunniffe, Pedro J. Diaz Payno, Robert T. Brady, Henrique V. Almeida, Simon F. Carroll, John M. O’Byrne, Daniel J. Kelly, Pieter AJ. Brama, Fergal J. O’ Brien
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomaterials and Biosystems
Subjects:
Tissue engineering
Collagen
In vivo
Osteochondral
Cartilage
Caprine model
Online Access:http://www.sciencedirect.com/science/article/pii/S2666534422000289

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