A complete theoretical framework for inferring horizontal gene transfers using partial order sets.

We present a method for detecting horizontal gene transfer (HGT) using partial orders (posets). The method requires a poset for each species/gene pair, where we have a set of species S, and a set of genes G. Given the posets, the method constructs a phylogenetic tree that is compatible with the set...

Full description

Bibliographic Details
Main Authors: Nahla A Belal, Lenwood S Heath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0281824
_version_ 1797843053392691200
author Nahla A Belal
Lenwood S Heath
author_facet Nahla A Belal
Lenwood S Heath
author_sort Nahla A Belal
collection DOAJ
description We present a method for detecting horizontal gene transfer (HGT) using partial orders (posets). The method requires a poset for each species/gene pair, where we have a set of species S, and a set of genes G. Given the posets, the method constructs a phylogenetic tree that is compatible with the set of posets; this is done for each gene. Also, the set of posets can be derived from the tree. The trees constructed for each gene are then compared and tested for contradicting information, where a contradiction suggests HGT.
first_indexed 2024-04-09T16:58:16Z
format Article
id doaj.art-8d084e78f5544008bc1191a4e5f1b68e
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-04-09T16:58:16Z
publishDate 2023-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-8d084e78f5544008bc1191a4e5f1b68e2023-04-21T05:34:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01183e028182410.1371/journal.pone.0281824A complete theoretical framework for inferring horizontal gene transfers using partial order sets.Nahla A BelalLenwood S HeathWe present a method for detecting horizontal gene transfer (HGT) using partial orders (posets). The method requires a poset for each species/gene pair, where we have a set of species S, and a set of genes G. Given the posets, the method constructs a phylogenetic tree that is compatible with the set of posets; this is done for each gene. Also, the set of posets can be derived from the tree. The trees constructed for each gene are then compared and tested for contradicting information, where a contradiction suggests HGT.https://doi.org/10.1371/journal.pone.0281824
spellingShingle Nahla A Belal
Lenwood S Heath
A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
PLoS ONE
title A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
title_full A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
title_fullStr A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
title_full_unstemmed A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
title_short A complete theoretical framework for inferring horizontal gene transfers using partial order sets.
title_sort complete theoretical framework for inferring horizontal gene transfers using partial order sets
url https://doi.org/10.1371/journal.pone.0281824
work_keys_str_mv AT nahlaabelal acompletetheoreticalframeworkforinferringhorizontalgenetransfersusingpartialordersets
AT lenwoodsheath acompletetheoreticalframeworkforinferringhorizontalgenetransfersusingpartialordersets
AT nahlaabelal completetheoreticalframeworkforinferringhorizontalgenetransfersusingpartialordersets
AT lenwoodsheath completetheoreticalframeworkforinferringhorizontalgenetransfersusingpartialordersets