Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change

Purpose: We report a case of bilateral severe pigmentary glaucoma and paracentral acute middle maculopathy (PAMM) following laser treatment for iris color change. Observations: A 32-year-old female presented to our emergency clinic after having undergone 4 sessions of bilateral cosmetic iris laser t...

Full description

Bibliographic Details
Main Authors: Jiaru Liu, Salim Korban, Marlene R. Moster, Marc-André Rhéaume, Qianqian Wang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993623001354
_version_ 1827591553228472320
author Jiaru Liu
Salim Korban
Marlene R. Moster
Marc-André Rhéaume
Qianqian Wang
author_facet Jiaru Liu
Salim Korban
Marlene R. Moster
Marc-André Rhéaume
Qianqian Wang
author_sort Jiaru Liu
collection DOAJ
description Purpose: We report a case of bilateral severe pigmentary glaucoma and paracentral acute middle maculopathy (PAMM) following laser treatment for iris color change. Observations: A 32-year-old female presented to our emergency clinic after having undergone 4 sessions of bilateral cosmetic iris laser treatment in Turkey to lighten the color of her dark brown irides. Visual acuity was 20/150 in the right eye (OD) and counting fingers in the left eye (OS) at presentation. Intraocular pressures (IOP) were 50 mmHg in the right eye and 42 mmHg in the left eye, with 4+ free-floating pigmented cells in the anterior chamber. The fundus exam revealed cup-to-disc ratios of 0.5 in the right eye and 0.35 in the left eye and scattered intraretinal hemorrhages in both eyes. The diagnoses of bilateral severe iatrogenic pigmentary glaucoma and PAMM were established. Urgent bilateral fornix-based trabeculectomies with mitomycin C (MMC) 0.05% were performed with an attempt to wash out as much pigment from the anterior chamber as possible. Post-operatively, despite well-controlled IOP and cessation of all glaucoma medications, the patient remains with visual field defects and significant glare. Conclusions and Importance: Photoablative iridoplasty is rarely encountered as a cause of iatrogenic pigmentary glaucoma in North American due to strict regulations against this procedure. However, physicians must be aware of its devastating and life-changing visual sequelae and elicit a careful history in patients with a similar presentation. Our patient demonstrated acute, severe glaucomatous damage from pigmentary dispersion along with PAMM, a newly described complication of this procedure. We strongly advise against this medically unnecessary practice.
first_indexed 2024-03-09T01:34:22Z
format Article
id doaj.art-8d0c9e201f4b42b1bd6e49eeccc3186e
institution Directory Open Access Journal
issn 2451-9936
language English
last_indexed 2024-03-09T01:34:22Z
publishDate 2023-12-01
publisher Elsevier
record_format Article
series American Journal of Ophthalmology Case Reports
spelling doaj.art-8d0c9e201f4b42b1bd6e49eeccc3186e2023-12-09T06:07:17ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362023-12-0132101927Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color changeJiaru Liu0Salim Korban1Marlene R. Moster2Marc-André Rhéaume3Qianqian Wang4Department of Ophthalmology, University of Montreal, Montreal, Quebec, CanadaDepartment of Ophthalmology, University of Montreal, Montreal, Quebec, CanadaGlaucoma Service, Wills Eye Hospital, Philadelphia, PA, USA; Sidney Kimmel Medical Collage, Thomas Jefferson University, Philadelphia, PA, USADepartment of Ophthalmology, University of Montreal, Montreal, Quebec, Canada; Department of Ophthalmology, University of Montreal Hospital Center, Montreal, Quebec, CanadaDepartment of Ophthalmology, University of Montreal, Montreal, Quebec, Canada; Department of Ophthalmology, University of Montreal Hospital Center, Montreal, Quebec, Canada; Corresponding author. University of Montreal Health Center (CHUM), 1000, rue Saint-Denis, Pavillon D - 1er étage - D0120, Montréal, QC, H2X 0C1, Canada.Purpose: We report a case of bilateral severe pigmentary glaucoma and paracentral acute middle maculopathy (PAMM) following laser treatment for iris color change. Observations: A 32-year-old female presented to our emergency clinic after having undergone 4 sessions of bilateral cosmetic iris laser treatment in Turkey to lighten the color of her dark brown irides. Visual acuity was 20/150 in the right eye (OD) and counting fingers in the left eye (OS) at presentation. Intraocular pressures (IOP) were 50 mmHg in the right eye and 42 mmHg in the left eye, with 4+ free-floating pigmented cells in the anterior chamber. The fundus exam revealed cup-to-disc ratios of 0.5 in the right eye and 0.35 in the left eye and scattered intraretinal hemorrhages in both eyes. The diagnoses of bilateral severe iatrogenic pigmentary glaucoma and PAMM were established. Urgent bilateral fornix-based trabeculectomies with mitomycin C (MMC) 0.05% were performed with an attempt to wash out as much pigment from the anterior chamber as possible. Post-operatively, despite well-controlled IOP and cessation of all glaucoma medications, the patient remains with visual field defects and significant glare. Conclusions and Importance: Photoablative iridoplasty is rarely encountered as a cause of iatrogenic pigmentary glaucoma in North American due to strict regulations against this procedure. However, physicians must be aware of its devastating and life-changing visual sequelae and elicit a careful history in patients with a similar presentation. Our patient demonstrated acute, severe glaucomatous damage from pigmentary dispersion along with PAMM, a newly described complication of this procedure. We strongly advise against this medically unnecessary practice.http://www.sciencedirect.com/science/article/pii/S2451993623001354GlaucomaPigment dispersionPhotoablative iridoplastyMaculopathy
spellingShingle Jiaru Liu
Salim Korban
Marlene R. Moster
Marc-André Rhéaume
Qianqian Wang
Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
American Journal of Ophthalmology Case Reports
Glaucoma
Pigment dispersion
Photoablative iridoplasty
Maculopathy
title Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
title_full Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
title_fullStr Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
title_full_unstemmed Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
title_short Bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
title_sort bilateral severe iatrogenic pigmentary glaucoma following laser treatment for cosmetic iris color change
topic Glaucoma
Pigment dispersion
Photoablative iridoplasty
Maculopathy
url http://www.sciencedirect.com/science/article/pii/S2451993623001354
work_keys_str_mv AT jiaruliu bilateralsevereiatrogenicpigmentaryglaucomafollowinglasertreatmentforcosmeticiriscolorchange
AT salimkorban bilateralsevereiatrogenicpigmentaryglaucomafollowinglasertreatmentforcosmeticiriscolorchange
AT marlenermoster bilateralsevereiatrogenicpigmentaryglaucomafollowinglasertreatmentforcosmeticiriscolorchange
AT marcandrerheaume bilateralsevereiatrogenicpigmentaryglaucomafollowinglasertreatmentforcosmeticiriscolorchange
AT qianqianwang bilateralsevereiatrogenicpigmentaryglaucomafollowinglasertreatmentforcosmeticiriscolorchange