CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION

Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval p...

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Main Authors: N. V. Furman, S. S. Shmatova
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/10
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author N. V. Furman
S. S. Shmatova
author_facet N. V. Furman
S. S. Shmatova
author_sort N. V. Furman
collection DOAJ
description Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation. List of drugs that cause QT prolongation is constantly growing and being updated. The review contains current data on the clinical significance of the control of QT interval duration within drug therapy. Clinical conditions associated with an increased risk of QT interval prolongation are described. Drugs that can induce QT prolongation are also discussed.
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spelling doaj.art-8d0dbc766d154616850653292f4e29662024-04-01T07:43:20ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019331131510.20996/1819-6446-2013-9-3-311-31510CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATIONN. V. Furman0S. S. Shmatova1Saratov Research Institute of Cardiology, SaratovSaratov Research Institute of Cardiology, SaratovInterval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation. List of drugs that cause QT prolongation is constantly growing and being updated. The review contains current data on the clinical significance of the control of QT interval duration within drug therapy. Clinical conditions associated with an increased risk of QT interval prolongation are described. Drugs that can induce QT prolongation are also discussed.https://www.rpcardio.online/jour/article/view/10long qt syndromepolymorphic ventricular tachycardiatorsade de pointeslife-threatening arrhythmias
spellingShingle N. V. Furman
S. S. Shmatova
CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
Рациональная фармакотерапия в кардиологии
long qt syndrome
polymorphic ventricular tachycardia
torsade de pointes
life-threatening arrhythmias
title CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
title_full CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
title_fullStr CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
title_full_unstemmed CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
title_short CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION
title_sort clinical significance of druginduced intervals qt and qtc prolongation
topic long qt syndrome
polymorphic ventricular tachycardia
torsade de pointes
life-threatening arrhythmias
url https://www.rpcardio.online/jour/article/view/10
work_keys_str_mv AT nvfurman clinicalsignificanceofdruginducedintervalsqtandqtcprolongation
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