SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin

SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin

Abstract Renal Cell Carcinoma (RCC) is the most common form of all renal cancer cases, and well-known for its highly aggressive metastatic behavior. SMOC2 is a recently described non-structural component of the extracellular matrix (ECM) that is highly expressed during tissue remodeling processes wi...

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Bibliographic Details
Main Authors: Daniel Feng, Peng Gao, Nathalie Henley, Marion Dubuissez, Nan Chen, Louis-Philippe Laurin, Virginie Royal, Vincent Pichette, Casimiro Gerarduzzi
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05059-2

Internet

https://doi.org/10.1038/s41419-022-05059-2

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