Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs) act via Smads 1, 5 and 8 and TGF-βs signal through Smads 2 and 3. The endocytic adaptor protein Eps15R, or ‘epidermal growth factor (EGF) receptor pathway substrate 15-relat...

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Bibliographic Details
Main Authors:	Elizabeth M. Callery, Chong Yon Park, Xin Xu, Haitao Zhu, James C. Smith, Gerald H. Thomsen
Format:	Article
Language:	English
Published:	The Royal Society 2012-01-01
Series:	Open Biology
Subjects:	eps15r smad bone morphogenetic protein endocytosis bimolecular fluorescence complementation
Online Access:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120060

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