Comparative efficacy and safety of JAK inhibitors as monotherapy and in combination with methotrexate in patients with active rheumatoid arthritis: A systematic review and meta-analysis
BackgroundWe aim to evaluate the efficacy and tolerability of Janus kinase inhibitors (JAKi) as monotherapy and in combination with methotrexate (MTX) in active rheumatoid arthritis (RA).MethodsMedline, EMBASE, and Cochrane Library were systematically searched to identify relevant randomized control...
Main Authors: | Li Liu, Yi-Dan Yan, Fang-Hong Shi, Hou-Wen Lin, Zhi-Chun Gu, Jia Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.977265/full |
Similar Items
-
JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future
by: Jacopo Angelini, et al.
Published: (2020-07-01) -
EFFICIENCY OF TRIPLE (METHOTREXATE + SULFASALAZINE + HYDROXYCHLOROQUINE) COMBINATION DISEASE-MODIFYING THERAPY VERSUS METOTREXATE MONOTHERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS
by: E E Gubar', et al.
Published: (2011-04-01) -
Effectiveness of iguratimod as monotherapy or combined therapy in patients with rheumatoid arthritis: a systematic review and meta-analysis of RCTs
by: Chao-Jun Hu, et al.
Published: (2021-07-01) -
Methotrexate intolerance in Rheumatoid Arthritis
by: Harjit Singh Nalwa, et al.
Published: (2023-03-01) -
Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis
by: Sytske Anne Bergstra, et al.
Published: (2017-11-01)