Cell membrane-coated nanomaterials for cancer therapy
With the development of nanotechnology, nanoparticles have emerged as a delivery carrier for tumor drug therapy, which can improve the therapeutic effect by increasing the stability and solubility and prolonging the half-life of drugs. However, nanoparticles are foreign substances for humans, are ea...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Materials Today Bio |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006423000935 |
| _version_ | 1797796405695217664 |
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| author | Shiying Zeng Qinglai Tang Minna Xiao Xinying Tong Tao Yang Danhui Yin Lanjie Lei Shisheng Li |
| author_facet | Shiying Zeng Qinglai Tang Minna Xiao Xinying Tong Tao Yang Danhui Yin Lanjie Lei Shisheng Li |
| author_sort | Shiying Zeng |
| collection | DOAJ |
| description | With the development of nanotechnology, nanoparticles have emerged as a delivery carrier for tumor drug therapy, which can improve the therapeutic effect by increasing the stability and solubility and prolonging the half-life of drugs. However, nanoparticles are foreign substances for humans, are easily cleared by the immune system, are less targeted to tumors, and may even be toxic to the body. As a natural biological material, cell membranes have unique biological properties, such as good biocompatibility, strong targeting ability, the ability to evade immune surveillance, and high drug-carrying capacity. In this article, we review cell membrane-coated nanoparticles (CMNPs) and their applications to tumor therapy. First, we briefly describe CMNP characteristics and applications. Second, we present the characteristics and advantages of different cell membranes as well as nanoparticles, provide a brief description of the process of CMNPs, discuss the current status of their application to tumor therapy, summarize their shortcomings for use in cancer therapy, and propose future research directions. This review summarizes the research progress on CMNPs in cancer therapy in recent years and assesses remaining problems, providing scholars with new ideas for future research on CMNPs in tumor therapy. |
| first_indexed | 2024-03-13T03:32:35Z |
| format | Article |
| id | doaj.art-8d253ffb33674fd8b685367c87cf5fff |
| institution | Directory Open Access Journal |
| issn | 2590-0064 |
| language | English |
| last_indexed | 2024-03-13T03:32:35Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj.art-8d253ffb33674fd8b685367c87cf5fff2023-06-24T05:18:35ZengElsevierMaterials Today Bio2590-00642023-06-0120100633Cell membrane-coated nanomaterials for cancer therapyShiying Zeng0Qinglai Tang1Minna Xiao2Xinying Tong3Tao Yang4Danhui Yin5Lanjie Lei6Shisheng Li7Department of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaDepartment of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaDepartment of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaDepartment of Hemodialysis, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaDepartment of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaDepartment of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, ChinaState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China; Corresponding author.Department of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, China; Corresponding author.With the development of nanotechnology, nanoparticles have emerged as a delivery carrier for tumor drug therapy, which can improve the therapeutic effect by increasing the stability and solubility and prolonging the half-life of drugs. However, nanoparticles are foreign substances for humans, are easily cleared by the immune system, are less targeted to tumors, and may even be toxic to the body. As a natural biological material, cell membranes have unique biological properties, such as good biocompatibility, strong targeting ability, the ability to evade immune surveillance, and high drug-carrying capacity. In this article, we review cell membrane-coated nanoparticles (CMNPs) and their applications to tumor therapy. First, we briefly describe CMNP characteristics and applications. Second, we present the characteristics and advantages of different cell membranes as well as nanoparticles, provide a brief description of the process of CMNPs, discuss the current status of their application to tumor therapy, summarize their shortcomings for use in cancer therapy, and propose future research directions. This review summarizes the research progress on CMNPs in cancer therapy in recent years and assesses remaining problems, providing scholars with new ideas for future research on CMNPs in tumor therapy.http://www.sciencedirect.com/science/article/pii/S2590006423000935Cell membraneNanomaterialsCancer therapyNanotechnology |
| spellingShingle | Shiying Zeng Qinglai Tang Minna Xiao Xinying Tong Tao Yang Danhui Yin Lanjie Lei Shisheng Li Cell membrane-coated nanomaterials for cancer therapy Materials Today Bio Cell membrane Nanomaterials Cancer therapy Nanotechnology |
| title | Cell membrane-coated nanomaterials for cancer therapy |
| title_full | Cell membrane-coated nanomaterials for cancer therapy |
| title_fullStr | Cell membrane-coated nanomaterials for cancer therapy |
| title_full_unstemmed | Cell membrane-coated nanomaterials for cancer therapy |
| title_short | Cell membrane-coated nanomaterials for cancer therapy |
| title_sort | cell membrane coated nanomaterials for cancer therapy |
| topic | Cell membrane Nanomaterials Cancer therapy Nanotechnology |
| url | http://www.sciencedirect.com/science/article/pii/S2590006423000935 |
| work_keys_str_mv | AT shiyingzeng cellmembranecoatednanomaterialsforcancertherapy AT qinglaitang cellmembranecoatednanomaterialsforcancertherapy AT minnaxiao cellmembranecoatednanomaterialsforcancertherapy AT xinyingtong cellmembranecoatednanomaterialsforcancertherapy AT taoyang cellmembranecoatednanomaterialsforcancertherapy AT danhuiyin cellmembranecoatednanomaterialsforcancertherapy AT lanjielei cellmembranecoatednanomaterialsforcancertherapy AT shishengli cellmembranecoatednanomaterialsforcancertherapy |