CD8TCEI-EukPath: A Novel Predictor to Rapidly Identify CD8+ T-Cell Epitopes of Eukaryotic Pathogens Using a Hybrid Feature Selection Approach

CD8TCEI-EukPath: A Novel Predictor to Rapidly Identify CD8+ T-Cell Epitopes of Eukaryotic Pathogens Using a Hybrid Feature Selection Approach

Computational prediction to screen potential vaccine candidates has been proven to be a reliable way to provide guarantees for vaccine discovery in infectious diseases. As an important class of organisms causing infectious diseases, pathogenic eukaryotes (such as parasitic protozoans) have evolved t...

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Bibliographic Details
Main Authors: Rui-Si Hu, Jin Wu, Lichao Zhang, Xun Zhou, Ying Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
eukaryotic pathogens
T-cell epitopes
machine learning
hybrid features
LightGBM
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.935989/full

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