Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection

Severe acute respiratory syndrome coronavirus 2 readily transmits between domestic cats. We found that domestic cats that recover from an initial infection might be protected from reinfection. However, we found long-term persistence of inflammation and other lung lesions after infection, despite a l...

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Main Authors: Shiho Chiba, Peter J. Halfmann, Masato Hatta, Tadashi Maemura, Shufang Fan, Tammy Armbrust, Olivia M. Swartley, LaTasha K. Crawford, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2021-02-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/27/2/20-3884_article
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author Shiho Chiba
Peter J. Halfmann
Masato Hatta
Tadashi Maemura
Shufang Fan
Tammy Armbrust
Olivia M. Swartley
LaTasha K. Crawford
Yoshihiro Kawaoka
author_facet Shiho Chiba
Peter J. Halfmann
Masato Hatta
Tadashi Maemura
Shufang Fan
Tammy Armbrust
Olivia M. Swartley
LaTasha K. Crawford
Yoshihiro Kawaoka
author_sort Shiho Chiba
collection DOAJ
description Severe acute respiratory syndrome coronavirus 2 readily transmits between domestic cats. We found that domestic cats that recover from an initial infection might be protected from reinfection. However, we found long-term persistence of inflammation and other lung lesions after infection, despite a lack of clinical symptoms and limited viral replication in the lungs.
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spelling doaj.art-8d2796af5b9f47a58a96fc41ebd380162022-12-21T21:09:54ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592021-02-0127266066310.3201/eid2702.203884Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 InfectionShiho ChibaPeter J. HalfmannMasato HattaTadashi MaemuraShufang FanTammy ArmbrustOlivia M. SwartleyLaTasha K. CrawfordYoshihiro KawaokaSevere acute respiratory syndrome coronavirus 2 readily transmits between domestic cats. We found that domestic cats that recover from an initial infection might be protected from reinfection. However, we found long-term persistence of inflammation and other lung lesions after infection, despite a lack of clinical symptoms and limited viral replication in the lungs.https://wwwnc.cdc.gov/eid/article/27/2/20-3884_articleCOVID-19coronavirus diseaseSARS-CoV-2severe acute respiratory syndrome coronavirus 2virusesrespiratory infections
spellingShingle Shiho Chiba
Peter J. Halfmann
Masato Hatta
Tadashi Maemura
Shufang Fan
Tammy Armbrust
Olivia M. Swartley
LaTasha K. Crawford
Yoshihiro Kawaoka
Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
Emerging Infectious Diseases
COVID-19
coronavirus disease
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
viruses
respiratory infections
title Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
title_full Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
title_fullStr Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
title_full_unstemmed Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
title_short Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection
title_sort protective immunity and persistent lung sequelae in domestic cats after sars cov 2 infection
topic COVID-19
coronavirus disease
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
viruses
respiratory infections
url https://wwwnc.cdc.gov/eid/article/27/2/20-3884_article
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