Desert Hedgehog/Patch2 axis contributes to vascular permeability and angiogenesis in glioblastoma

Desert Hedgehog/Patch2 axis contributes to vascular permeability and angiogenesis in glioblastoma

Glioblastoma multiforme (GBM) constitutes the most common and the most aggressive type of human tumors affecting the central nervous system. Prognosis remains dark due to the inefficiency of current treatments and the rapid relapse. Paralleling other human tumors, GBM contains a fraction of tumor in...

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Bibliographic Details
Main Authors:	Sandy eAzzi, Lucas eTreps, Heloise M Leclair, Hai-Mi eNgo, Elizabeth eHarford-Wright, Julie eGAVARD
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-11-01
Series:	Frontiers in Pharmacology
Subjects:	Glioma Permeability tumor vasculature Brain endothelial cells Hedghog
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00281/full

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