Perspective: The Challenge of Clinical Decision-Making for Drug Treatment in Older People. The Role of Multidimensional Assessment and Prognosis

Perspective: The Challenge of Clinical Decision-Making for Drug Treatment in Older People. The Role of Multidimensional Assessment and Prognosis

A complex decision path with a careful evaluation of the risk-benefit ratio is mandatory for drug treatment in advanced age. Enrolment biases in randomized clinical trials (RCTs) cause an underrepresentation of older individuals. In high-risk frail older subjects, the lack of RCTs makes clinical dec...

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Bibliographic Details
Main Authors: Alberto ePilotto, Daniele eSancarlo, Julia eDaragjati, Francesco ePanza
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Medicine
Subjects:
clinical decision-making
Frailty
Older age
Prognostic indices
comprehensive geriatric assessmen
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00061/full

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