Quantitative Comparison of Conventional and t-SNE-guided Gating Analyses

Quantitative Comparison of Conventional and t-SNE-guided Gating Analyses

Dimensionality reduction using the t-Distributed Stochastic Neighbor Embedding (t-SNE) algorithm has emerged as a popular tool for visualizing high-parameter single-cell data. While this approach has obvious potential for data visualization it remains unclear how t-SNE analysis compares to conventio...

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Bibliographic Details
Main Authors: Shadi Toghi Eshghi, Amelia Au-Yeung, Chikara Takahashi, Christopher R. Bolen, Maclean N. Nyachienga, Sean P. Lear, Cherie Green, W. Rodney Mathews, William E. O'Gorman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
cyTOF
t-SNE
cytometry informatics
dimensionality reduction
immunophenotyping
high-dimensional cytometry
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01194/full

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