Hedgehog Signaling: An Achilles’ Heel in Cancer
Hedgehog signaling pathway originally identified in the fruit fly Drosophila is an evolutionarily conserved signaling mechanism with crucial roles in embryogenesis, growth and patterning. It exerts its biological effect through a signaling mechanism that terminates at glioma-associated oncogene (GLI...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-10-01
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Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523319301998 |