Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE
Abstract Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant’s longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally effi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-56327-4 |
| _version_ | 1797266850454700032 |
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| author | Patrik Müller Alexander Synek Timo Stauß Carl Steinnagel Tobias Ehlers Paul Christoph Gembarski Dieter Pahr Roland Lachmayer |
| author_facet | Patrik Müller Alexander Synek Timo Stauß Carl Steinnagel Tobias Ehlers Paul Christoph Gembarski Dieter Pahr Roland Lachmayer |
| author_sort | Patrik Müller |
| collection | DOAJ |
| description | Abstract Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant’s longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally efficient method for density-based topology optimization of homogenized lattice structures in a patient-specific hip endoprosthesis. Thus, the root mean square error (RMSE) of the stress deviations between the physiological femur model and the optimized total hip arthroplasty (THA) model compared to an unoptimized-THA model could be reduced by 81 % and 66 % in Gruen zone (GZ) 6 and 7. However, the method relies on homogenized finite element (FE) models that only use a simplified representation of the microstructural geometry of the bone and implant. The topology-optimized hip endoprosthesis with graded lattice structures was synthesized using algorithmic design and analyzed in a virtual implanted state using micro-finite element (micro-FE) analysis to validate the optimization method. Homogenized FE and micro-FE models were compared based on averaged von Mises stresses in multiple regions of interest. A strong correlation (CCC > 0.97) was observed, indicating that optimizing homogenized lattice structures yields reliable outcomes. The graded implant was additively manufactured to ensure the topology-optimized result’s feasibility. |
| first_indexed | 2024-04-25T01:07:14Z |
| format | Article |
| id | doaj.art-8d30583046674582ab0c47b418069885 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-25T01:07:14Z |
| publishDate | 2024-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-8d30583046674582ab0c47b4180698852024-03-10T12:11:32ZengNature PortfolioScientific Reports2045-23222024-03-0114111410.1038/s41598-024-56327-4Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FEPatrik Müller0Alexander Synek1Timo Stauß2Carl Steinnagel3Tobias Ehlers4Paul Christoph Gembarski5Dieter Pahr6Roland Lachmayer7Institute of Product Development, Leibniz University of HannoverTU Wien, Institute for Lightweight Design and Structural BiomechanicsInstitute of Product Development, Leibniz University of HannoverInstitute of Product Development, Leibniz University of HannoverInstitute of Product Development, Leibniz University of HannoverInstitute of Product Development, Leibniz University of HannoverTU Wien, Institute for Lightweight Design and Structural BiomechanicsInstitute of Product Development, Leibniz University of HannoverAbstract Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant’s longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally efficient method for density-based topology optimization of homogenized lattice structures in a patient-specific hip endoprosthesis. Thus, the root mean square error (RMSE) of the stress deviations between the physiological femur model and the optimized total hip arthroplasty (THA) model compared to an unoptimized-THA model could be reduced by 81 % and 66 % in Gruen zone (GZ) 6 and 7. However, the method relies on homogenized finite element (FE) models that only use a simplified representation of the microstructural geometry of the bone and implant. The topology-optimized hip endoprosthesis with graded lattice structures was synthesized using algorithmic design and analyzed in a virtual implanted state using micro-finite element (micro-FE) analysis to validate the optimization method. Homogenized FE and micro-FE models were compared based on averaged von Mises stresses in multiple regions of interest. A strong correlation (CCC > 0.97) was observed, indicating that optimizing homogenized lattice structures yields reliable outcomes. The graded implant was additively manufactured to ensure the topology-optimized result’s feasibility.https://doi.org/10.1038/s41598-024-56327-4Individualized hip endoprosthesisLattice structuresTopology optimizationMicro-FEAdditive manufacturing |
| spellingShingle | Patrik Müller Alexander Synek Timo Stauß Carl Steinnagel Tobias Ehlers Paul Christoph Gembarski Dieter Pahr Roland Lachmayer Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE Scientific Reports Individualized hip endoprosthesis Lattice structures Topology optimization Micro-FE Additive manufacturing |
| title | Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE |
| title_full | Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE |
| title_fullStr | Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE |
| title_full_unstemmed | Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE |
| title_short | Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE |
| title_sort | development of a density based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro fe |
| topic | Individualized hip endoprosthesis Lattice structures Topology optimization Micro-FE Additive manufacturing |
| url | https://doi.org/10.1038/s41598-024-56327-4 |
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