Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities
Herbal tea has numerous biological activities and exhibits broad benefits for human health. In China, the flower buds of <i>Lyonia ovalifolia</i> are traditionally processed as herbal tea, namely White Que Zui tea (WQT). This study was aimed to evaluate the effect of ultra-high hydrostat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/3/628 |
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| author | Xiaoyu Zhang Mengcheng Li Li Zhen Yudan Wang Yifen Wang Yuyue Qin Zhihong Zhang Tianrui Zhao Jianxin Cao Yaping Liu Guiguang Cheng |
| author_facet | Xiaoyu Zhang Mengcheng Li Li Zhen Yudan Wang Yifen Wang Yuyue Qin Zhihong Zhang Tianrui Zhao Jianxin Cao Yaping Liu Guiguang Cheng |
| author_sort | Xiaoyu Zhang |
| collection | DOAJ |
| description | Herbal tea has numerous biological activities and exhibits broad benefits for human health. In China, the flower buds of <i>Lyonia ovalifolia</i> are traditionally processed as herbal tea, namely White Que Zui tea (WQT). This study was aimed to evaluate the effect of ultra-high hydrostatic pressure (UHHP) pretreatment on the chemical constituents and biological activities of free, esterified, and insoluble-bound phenolic fractions from WQT. A total of 327 chemical constituents were identified by a quasi-targeted metabolomics analysis. UHHP pretreatment extremely inhibited reactive oxygen species (ROS) production and cell apoptosis in H<sub>2</sub>O<sub>2</sub>-induced HepG2 cells, and it increased the activities of intracellular antioxidant enzymes (SOD and CAT) and GSH content in different phenolic fractions from WQT. In addition, after UHHP pretreatment, the anti-inflammatory effects of different phenolic fractions from WQT were improved by inhibiting the production of nitric oxide (NO) and pro-inflammatory cytokines (TNF-α, IL-6, and IL-1<i>β</i>) in LPS-induced RAW264.7 cells. Thus, the UHHP method might be a potential pretreatment strategy for improving the bioavailability of phytochemicals from natural plants. |
| first_indexed | 2024-03-11T09:44:04Z |
| format | Article |
| id | doaj.art-8d32c8ac4d46449488a7e8b2c13b9c2d |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-11T09:44:04Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-8d32c8ac4d46449488a7e8b2c13b9c2d2023-11-16T16:42:03ZengMDPI AGFoods2304-81582023-02-0112362810.3390/foods12030628Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory ActivitiesXiaoyu Zhang0Mengcheng Li1Li Zhen2Yudan Wang3Yifen Wang4Yuyue Qin5Zhihong Zhang6Tianrui Zhao7Jianxin Cao8Yaping Liu9Guiguang Cheng10The Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaKunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650000, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food and Bioengineering, Jiangsu University, Zhenjiang 212013, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaThe Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, ChinaHerbal tea has numerous biological activities and exhibits broad benefits for human health. In China, the flower buds of <i>Lyonia ovalifolia</i> are traditionally processed as herbal tea, namely White Que Zui tea (WQT). This study was aimed to evaluate the effect of ultra-high hydrostatic pressure (UHHP) pretreatment on the chemical constituents and biological activities of free, esterified, and insoluble-bound phenolic fractions from WQT. A total of 327 chemical constituents were identified by a quasi-targeted metabolomics analysis. UHHP pretreatment extremely inhibited reactive oxygen species (ROS) production and cell apoptosis in H<sub>2</sub>O<sub>2</sub>-induced HepG2 cells, and it increased the activities of intracellular antioxidant enzymes (SOD and CAT) and GSH content in different phenolic fractions from WQT. In addition, after UHHP pretreatment, the anti-inflammatory effects of different phenolic fractions from WQT were improved by inhibiting the production of nitric oxide (NO) and pro-inflammatory cytokines (TNF-α, IL-6, and IL-1<i>β</i>) in LPS-induced RAW264.7 cells. Thus, the UHHP method might be a potential pretreatment strategy for improving the bioavailability of phytochemicals from natural plants.https://www.mdpi.com/2304-8158/12/3/628<i>Lyonia ovalifolia</i>ultra-high hydrostatic pressure pretreatmentUHPLC-MS/MS analysisantioxidant activityanti-inflammatory activity |
| spellingShingle | Xiaoyu Zhang Mengcheng Li Li Zhen Yudan Wang Yifen Wang Yuyue Qin Zhihong Zhang Tianrui Zhao Jianxin Cao Yaping Liu Guiguang Cheng Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities Foods <i>Lyonia ovalifolia</i> ultra-high hydrostatic pressure pretreatment UHPLC-MS/MS analysis antioxidant activity anti-inflammatory activity |
| title | Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities |
| title_full | Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities |
| title_fullStr | Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities |
| title_full_unstemmed | Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities |
| title_short | Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory Activities |
| title_sort | ultra high hydrostatic pressure pretreatment on white que zui tea chemical constituents antioxidant cytoprotective and anti inflammatory activities |
| topic | <i>Lyonia ovalifolia</i> ultra-high hydrostatic pressure pretreatment UHPLC-MS/MS analysis antioxidant activity anti-inflammatory activity |
| url | https://www.mdpi.com/2304-8158/12/3/628 |
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