Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)

Since influenza and coronaviruses are currently deadly and emerging threats worldwide, better treatment, remediation and prevention options are needed. In that regard, a basic understanding of severe acute respiratory syndrome (SARS)-CoV-2/COVID-19 (<i>Betacoronaviridae</i>) and other vi...

Full description

Bibliographic Details
Main Authors: Mark E. Obrenovich, Moncef B. Tayahi, Caryn L. Heidt, Steven N. Emancipator
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/10/12/2407
_version_ 1797456163620519936
author Mark E. Obrenovich
Moncef B. Tayahi
Caryn L. Heidt
Steven N. Emancipator
author_facet Mark E. Obrenovich
Moncef B. Tayahi
Caryn L. Heidt
Steven N. Emancipator
author_sort Mark E. Obrenovich
collection DOAJ
description Since influenza and coronaviruses are currently deadly and emerging threats worldwide, better treatment, remediation and prevention options are needed. In that regard, a basic understanding of severe acute respiratory syndrome (SARS)-CoV-2/COVID-19 (<i>Betacoronaviridae</i>) and other viral pathogen mechanisms of transmission are expected. Unfortunately, unprecedented, and growing distrust of vaccines and even masks or personal protective equipment (PPE) in the United States and elsewhere presents itself as an added challenge. We postulate that development of improved and highly effective prophylactic measures, together with new life-saving therapies that do inhibit or otherwise treat infection of SARS-CoV-2, influenza and other viral pathogens, could be an adjunct measure to globally protect vulnerable individuals from pandemic threats. In this review, we share what we learned from the past COVID experience to offer a multifactorial and improved approach to current and future pandemic infections or threats using low-cost means.
first_indexed 2024-03-09T16:04:22Z
format Article
id doaj.art-8d432bcc801242c09d02b0f6e55f3259
institution Directory Open Access Journal
issn 2076-2607
language English
last_indexed 2024-03-09T16:04:22Z
publishDate 2022-12-01
publisher MDPI AG
record_format Article
series Microorganisms
spelling doaj.art-8d432bcc801242c09d02b0f6e55f32592023-11-24T16:48:35ZengMDPI AGMicroorganisms2076-26072022-12-011012240710.3390/microorganisms10122407Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)Mark E. Obrenovich0Moncef B. Tayahi1Caryn L. Heidt2Steven N. Emancipator3Department of Veteran’s Affairs Medical Center, Research Service, Cleveland, OH 44106, USAThe Gilgamesh Foundation for Medical Science and Research, Cleveland, OH 44116, USADepartment of Chemical Engineering, Michigan Technological University, Houghton, MI 49931, USADepartment of Pathology, Case Western Reserve University, Cleveland, OH 44106, USASince influenza and coronaviruses are currently deadly and emerging threats worldwide, better treatment, remediation and prevention options are needed. In that regard, a basic understanding of severe acute respiratory syndrome (SARS)-CoV-2/COVID-19 (<i>Betacoronaviridae</i>) and other viral pathogen mechanisms of transmission are expected. Unfortunately, unprecedented, and growing distrust of vaccines and even masks or personal protective equipment (PPE) in the United States and elsewhere presents itself as an added challenge. We postulate that development of improved and highly effective prophylactic measures, together with new life-saving therapies that do inhibit or otherwise treat infection of SARS-CoV-2, influenza and other viral pathogens, could be an adjunct measure to globally protect vulnerable individuals from pandemic threats. In this review, we share what we learned from the past COVID experience to offer a multifactorial and improved approach to current and future pandemic infections or threats using low-cost means.https://www.mdpi.com/2076-2607/10/12/2407SARS-CoV-2personal protective equipmentPPE prophylacticCOVID-19pandemicisoelectric point
spellingShingle Mark E. Obrenovich
Moncef B. Tayahi
Caryn L. Heidt
Steven N. Emancipator
Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
Microorganisms
SARS-CoV-2
personal protective equipment
PPE prophylactic
COVID-19
pandemic
isoelectric point
title Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
title_full Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
title_fullStr Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
title_full_unstemmed Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
title_short Prophylaxis and Remediation for Future Pandemic Pathogens—(Lessons from a Post-COVID World)
title_sort prophylaxis and remediation for future pandemic pathogens lessons from a post covid world
topic SARS-CoV-2
personal protective equipment
PPE prophylactic
COVID-19
pandemic
isoelectric point
url https://www.mdpi.com/2076-2607/10/12/2407
work_keys_str_mv AT markeobrenovich prophylaxisandremediationforfuturepandemicpathogenslessonsfromapostcovidworld
AT moncefbtayahi prophylaxisandremediationforfuturepandemicpathogenslessonsfromapostcovidworld
AT carynlheidt prophylaxisandremediationforfuturepandemicpathogenslessonsfromapostcovidworld
AT stevennemancipator prophylaxisandremediationforfuturepandemicpathogenslessonsfromapostcovidworld