Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis
Mucopolysaccharidosis is a series of rare diseases where a lack of an enzyme affecting mucopolysaccharides metabolism in the patients′ lysosome induces the intracellular deposition of the mucopolysaccharides, and causes ocular and organ-related complications. Ocular complications included corneal op...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Rare Diseases
2023-07-01
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| Series: | 罕见病研究 |
| Subjects: | |
| Online Access: | https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2023.03.018 |
| _version_ | 1797369952152322048 |
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| author | SHI Meipan SHI Caiping DU Chixin |
| author_facet | SHI Meipan SHI Caiping DU Chixin |
| author_sort | SHI Meipan |
| collection | DOAJ |
| description | Mucopolysaccharidosis is a series of rare diseases where a lack of an enzyme affecting mucopolysaccharides metabolism in the patients′ lysosome induces the intracellular deposition of the mucopolysaccharides, and causes ocular and organ-related complications. Ocular complications included corneal opacity, glaucoma, ametropia, strabismus, and chorioretinopathy. This review summarizes the mechanisms, clinical manifestations, specific ophthalmological examinations, and treatments for offering the ophthalmological knowledge to diagnose and begin treatment earlier. |
| first_indexed | 2024-03-08T17:54:25Z |
| format | Article |
| id | doaj.art-8d447e76524b47e68511e7106e8ee49b |
| institution | Directory Open Access Journal |
| issn | 2097-0501 |
| language | zho |
| last_indexed | 2024-03-08T17:54:25Z |
| publishDate | 2023-07-01 |
| publisher | Editorial Office of Journal of Rare Diseases |
| record_format | Article |
| series | 罕见病研究 |
| spelling | doaj.art-8d447e76524b47e68511e7106e8ee49b2024-01-02T05:51:09ZzhoEditorial Office of Journal of Rare Diseases罕见病研究2097-05012023-07-012345045410.12376/j.issn.2097-0501.2023.03.018Advances in the Diagnosis and Treatment for Ocular Complication on MucopolysaccharidosisSHI Meipan0SHI Caiping1DU Chixin2Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Ophthalmology, Children′s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaMucopolysaccharidosis is a series of rare diseases where a lack of an enzyme affecting mucopolysaccharides metabolism in the patients′ lysosome induces the intracellular deposition of the mucopolysaccharides, and causes ocular and organ-related complications. Ocular complications included corneal opacity, glaucoma, ametropia, strabismus, and chorioretinopathy. This review summarizes the mechanisms, clinical manifestations, specific ophthalmological examinations, and treatments for offering the ophthalmological knowledge to diagnose and begin treatment earlier.https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2023.03.018mucopolysaccharidosisocular complicationsdiagnosistreatment |
| spellingShingle | SHI Meipan SHI Caiping DU Chixin Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis 罕见病研究 mucopolysaccharidosis ocular complications diagnosis treatment |
| title | Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis |
| title_full | Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis |
| title_fullStr | Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis |
| title_full_unstemmed | Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis |
| title_short | Advances in the Diagnosis and Treatment for Ocular Complication on Mucopolysaccharidosis |
| title_sort | advances in the diagnosis and treatment for ocular complication on mucopolysaccharidosis |
| topic | mucopolysaccharidosis ocular complications diagnosis treatment |
| url | https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2023.03.018 |
| work_keys_str_mv | AT shimeipan advancesinthediagnosisandtreatmentforocularcomplicationonmucopolysaccharidosis AT shicaiping advancesinthediagnosisandtreatmentforocularcomplicationonmucopolysaccharidosis AT duchixin advancesinthediagnosisandtreatmentforocularcomplicationonmucopolysaccharidosis |