Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children
Abstract Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood. Although it requires timely detection and intervention, existing continuous performance tests (CPTs) have limited efficacy. Research suggests that eye movement could offer important...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-41654-9 |
| _version_ | 1797576630559834112 |
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| author | Dong Yun Lee Yunmi Shin Rae Woong Park Sun-Mi Cho Sora Han Changsoon Yoon Jaheui Choo Joo Min Shim Kahee Kim Sang-Won Jeon Seong-Ju Kim |
| author_facet | Dong Yun Lee Yunmi Shin Rae Woong Park Sun-Mi Cho Sora Han Changsoon Yoon Jaheui Choo Joo Min Shim Kahee Kim Sang-Won Jeon Seong-Ju Kim |
| author_sort | Dong Yun Lee |
| collection | DOAJ |
| description | Abstract Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood. Although it requires timely detection and intervention, existing continuous performance tests (CPTs) have limited efficacy. Research suggests that eye movement could offer important diagnostic information for ADHD. This study aimed to compare the performance of eye-tracking with that of CPTs, both alone and in combination, and to evaluate the effect of medication on eye movement and CPT outcomes. We recruited participants into an ADHD group and a healthy control group between July 2021 and March 2022 from among children aged 6–10 years (n = 30 per group). The integration of eye-tracking with CPTs produced higher values for the area under the receiver operating characteristic (AUC, 0.889) compared with using CPTs only (AUC, 0.769) for identifying patients with ADHD. The use of eye-tracking alone showed higher performance compare with the use of CPTs alone (AUC of EYE: 0.856, AUC of CPT: 0.769, p = 0.029). Follow-up analysis revealed that most eye-tracking and CPT indicators improved significantly after taking an ADHD medication. The use of eye movement scales could be used to differentiate children with ADHD, with the possibility that integrating eye movement scales and CPTs could improve diagnostic precision. |
| first_indexed | 2024-03-10T21:55:39Z |
| format | Article |
| id | doaj.art-8d4be8ecd879430ba8c05d99afcf1e74 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-10T21:55:39Z |
| publishDate | 2023-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-8d4be8ecd879430ba8c05d99afcf1e742023-11-19T13:09:00ZengNature PortfolioScientific Reports2045-23222023-09-0113111010.1038/s41598-023-41654-9Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in childrenDong Yun Lee0Yunmi Shin1Rae Woong Park2Sun-Mi Cho3Sora Han4Changsoon Yoon5Jaheui Choo6Joo Min Shim7Kahee Kim8Sang-Won Jeon9Seong-Ju Kim10Department of Biomedical Informatics, Ajou University School of MedicineDepartment of Psychiatry, Ajou University School of MedicineDepartment of Biomedical Informatics, Ajou University School of MedicineDepartment of Psychiatry, Ajou University School of MedicineDepartment of Psychiatry, Ajou University School of MedicineAjou University HospitalAjou University HospitalAjou University HospitalDepartment of Medical Sciences, Graduate School of Ajou UniversityDepartment of Psychiatry, Kangbuk Samsung Hospital, Sungkyunkwan University School of MedicineDepartment of Medical Sciences, Graduate School of Ajou UniversityAbstract Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood. Although it requires timely detection and intervention, existing continuous performance tests (CPTs) have limited efficacy. Research suggests that eye movement could offer important diagnostic information for ADHD. This study aimed to compare the performance of eye-tracking with that of CPTs, both alone and in combination, and to evaluate the effect of medication on eye movement and CPT outcomes. We recruited participants into an ADHD group and a healthy control group between July 2021 and March 2022 from among children aged 6–10 years (n = 30 per group). The integration of eye-tracking with CPTs produced higher values for the area under the receiver operating characteristic (AUC, 0.889) compared with using CPTs only (AUC, 0.769) for identifying patients with ADHD. The use of eye-tracking alone showed higher performance compare with the use of CPTs alone (AUC of EYE: 0.856, AUC of CPT: 0.769, p = 0.029). Follow-up analysis revealed that most eye-tracking and CPT indicators improved significantly after taking an ADHD medication. The use of eye movement scales could be used to differentiate children with ADHD, with the possibility that integrating eye movement scales and CPTs could improve diagnostic precision.https://doi.org/10.1038/s41598-023-41654-9 |
| spellingShingle | Dong Yun Lee Yunmi Shin Rae Woong Park Sun-Mi Cho Sora Han Changsoon Yoon Jaheui Choo Joo Min Shim Kahee Kim Sang-Won Jeon Seong-Ju Kim Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children Scientific Reports |
| title | Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children |
| title_full | Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children |
| title_fullStr | Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children |
| title_full_unstemmed | Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children |
| title_short | Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children |
| title_sort | use of eye tracking to improve the identification of attention deficit hyperactivity disorder in children |
| url | https://doi.org/10.1038/s41598-023-41654-9 |
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