Degree of dopaminergic degeneration measured by 99mTc-TRODAT-1 SPECT/CT imaging

Degree of dopaminergic degeneration measured by 99mTc-TRODAT-1 SPECT/CT imaging

To prevent and treat Parkinson’s disease in its early stages, it is essential to be able to detect the degree of early dopaminergic neuron degeneration. Dopamine transporters (DAT) in the striatum regulate synaptic dopamine levels, and striatal 99mTc-TRODAT-1 single-photon emission computed tomograp...

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Bibliographic Details
Main Authors: Ling Lin, Jing Ye, Han Zhang, Zhong-Fu Han, Zhi-Hong Zheng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Parkinson′s disease; 6-hydroxydopamine; dopaminergic degeneration; dopamine transporter; 99mTc-TRO-DAT-1; tyrosine hydroxylase; substantia nigra; striatum; single-photon emission computed tomography; apomorphine; neurodegeneration; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=7;spage=1281;epage=1287;aulast=Lin

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