The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions
Objective: To analyze the correlation between placenta related disease of pregnant women with antecedent hysteroscopic adhesiolysis due to intrauterine adhesions (IUA). Materials and methods: This is a single center, non-randomized, open-label, retrospective cohort Study. 74 patients who had adhesio...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-07-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455920301170 |
| _version_ | 1818265643076550656 |
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| author | Lu-ping Zhang Ming Wang Xiang Shang Qi Zhang Bao-jun Yang Yun Xu Jing-hua Li Li-min Feng |
| author_facet | Lu-ping Zhang Ming Wang Xiang Shang Qi Zhang Bao-jun Yang Yun Xu Jing-hua Li Li-min Feng |
| author_sort | Lu-ping Zhang |
| collection | DOAJ |
| description | Objective: To analyze the correlation between placenta related disease of pregnant women with antecedent hysteroscopic adhesiolysis due to intrauterine adhesions (IUA). Materials and methods: This is a single center, non-randomized, open-label, retrospective cohort Study. 74 patients who had adhesiolysis and hormone therapy for IUA and progressed into the third trimester were group A and 296 without IUA were group B. The main outcome measure is the incidence of placenta related disease including placenta accreta spectrum, placenta previa, placental abruption, intrauterine growth restriction (IUGR), and pregnancy-induced hypertension (PIH). The second outcome is the perinatal, and intrapartum complications. Results: Patients in group A had a higher frequency of prior pregnancy times (2.51 ± 1.56 vs.1.84 ± 1.06, p = 0.001) and lower frequency of prior delivery times (0.20 ± 0.41 vs. 1.30 ± 0.51, p < 0.05) than group B at baseline. At delivery, there is no difference between the incidence of PIH and IUGR between two groups. However, a significantly higher frequency of placenta accreta (17.6% vs. 1.4%, OR = 15.56, 95% CI 4.91–49.34), placenta increta (5.4% vs. 0.7%, OR = 8.4, 95% CI 1.51–46.78), placenta previa (8.1% vs. 2.0%, OR = 4.265, 95%CI1.33–13.63) and postpartum hemorrhage (21.6% vs. 3.4%, OR = 7.890, 95% CI 3.41–18.26) were observed in group A than in group B. Conclusions: Compared to general population, the rates of placenta accreta, placenta increta, placenta previa, postpartum hemorrhage are higher among the IUA patients after hysteroscopic adhesiolysis, and special attention is needed at the termination of the pregnancy. |
| first_indexed | 2024-12-12T19:54:04Z |
| format | Article |
| id | doaj.art-8d4cb9f71c37448b9c6f0035784e79eb |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-12T19:54:04Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-8d4cb9f71c37448b9c6f0035784e79eb2022-12-22T00:13:55ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592020-07-01594575579The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesionsLu-ping Zhang0Ming Wang1Xiang Shang2Qi Zhang3Bao-jun Yang4Yun Xu5Jing-hua Li6Li-min Feng7Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, ChinaDepartment of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China; Corresponding author. Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, NO.119, South Fourth Ring West Road, Fengtai District, Beijing, 100070, China. Fax: +10 59976610.Objective: To analyze the correlation between placenta related disease of pregnant women with antecedent hysteroscopic adhesiolysis due to intrauterine adhesions (IUA). Materials and methods: This is a single center, non-randomized, open-label, retrospective cohort Study. 74 patients who had adhesiolysis and hormone therapy for IUA and progressed into the third trimester were group A and 296 without IUA were group B. The main outcome measure is the incidence of placenta related disease including placenta accreta spectrum, placenta previa, placental abruption, intrauterine growth restriction (IUGR), and pregnancy-induced hypertension (PIH). The second outcome is the perinatal, and intrapartum complications. Results: Patients in group A had a higher frequency of prior pregnancy times (2.51 ± 1.56 vs.1.84 ± 1.06, p = 0.001) and lower frequency of prior delivery times (0.20 ± 0.41 vs. 1.30 ± 0.51, p < 0.05) than group B at baseline. At delivery, there is no difference between the incidence of PIH and IUGR between two groups. However, a significantly higher frequency of placenta accreta (17.6% vs. 1.4%, OR = 15.56, 95% CI 4.91–49.34), placenta increta (5.4% vs. 0.7%, OR = 8.4, 95% CI 1.51–46.78), placenta previa (8.1% vs. 2.0%, OR = 4.265, 95%CI1.33–13.63) and postpartum hemorrhage (21.6% vs. 3.4%, OR = 7.890, 95% CI 3.41–18.26) were observed in group A than in group B. Conclusions: Compared to general population, the rates of placenta accreta, placenta increta, placenta previa, postpartum hemorrhage are higher among the IUA patients after hysteroscopic adhesiolysis, and special attention is needed at the termination of the pregnancy.http://www.sciencedirect.com/science/article/pii/S1028455920301170Asherman's syndromePlacenta incretaPlacenta previaPostpartum hemorrhage |
| spellingShingle | Lu-ping Zhang Ming Wang Xiang Shang Qi Zhang Bao-jun Yang Yun Xu Jing-hua Li Li-min Feng The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions Taiwanese Journal of Obstetrics & Gynecology Asherman's syndrome Placenta increta Placenta previa Postpartum hemorrhage |
| title | The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| title_full | The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| title_fullStr | The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| title_full_unstemmed | The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| title_short | The incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| title_sort | incidence of placenta related disease after the hysteroscopic adhesiolysis in patients with intrauterine adhesions |
| topic | Asherman's syndrome Placenta increta Placenta previa Postpartum hemorrhage |
| url | http://www.sciencedirect.com/science/article/pii/S1028455920301170 |
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