Characterization and application of a lactate and branched chain amino acid metabolism related gene signature in a prognosis risk model for multiple myeloma

Characterization and application of a lactate and branched chain amino acid metabolism related gene signature in a prognosis risk model for multiple myeloma

Abstract Background About 10% of hematologic malignancies are multiple myeloma (MM), an untreatable cancer. Although lactate and branched-chain amino acids (BCAA) are involved in supporting various tumor growth, it is unknown whether they have any bearing on MM prognosis. Methods MM-related datasets...

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Bibliographic Details
Main Authors: Zhengyu Yu, Bingquan Qiu, Hui Zhou, Linfeng Li, Ting Niu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cancer Cell International
Subjects:
Multiple myeloma
Prognosis
Lactate
Branched-chain amino acids
Tumor microenvironment
Drug prediction
Online Access:https://doi.org/10.1186/s12935-023-03007-4

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