Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome

Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome

Primary immunodeficiency diseases (PIDs) are a group of rare inherited disorders affecting the immune system that can be conventionally treated with allogeneic hematopoietic stem cell transplantation and with experimental autologous gene therapy. With both approaches still facing important challenge...

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Bibliographic Details
Main Authors:	Asma Naseem, Zohar Steinberg, Alessia Cavazza
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Immunology
Subjects:	rare diseases primary immunodeficiency gene therapy genome editing CRISPR/Cas9 Wiskott-Aldrich syndrome
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.966084/full

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