Evaluation of a Salmonella vectored vaccine expressing Mycobacterium avium subsp. paratuberculosis antigens against challenge in a goat model.

Evaluation of a Salmonella vectored vaccine expressing Mycobacterium avium subsp. paratuberculosis antigens against challenge in a goat model.

Johnes disease (JD), caused by Mycobacterium avium subsp paratuberculosis (MAP), occurs worldwide as chronic granulomatous enteritis of domestic and wild ruminants. To develop a cost effective vaccine, in a previous study we constructed an attenuated Salmonella strain that expressed a fusion product...

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Bibliographic Details
Main Authors: Syed M Faisal, Falong Yan, Tsai-Tzu Chen, Nicodemus M Useh, Shanguang Guo, Weiwei Yan, Shih-Jon Wang, Amy L Glaser, Sean P McDonough, Bhupinder Singh, Yung-Fu Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3739776?pdf=render

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