A protocol for a randomised controlled, double-blind feasibility trial investigating fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetine, Learning and Memory in Epilepsy (FLAME trial)

A protocol for a randomised controlled, double-blind feasibility trial investigating fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetine, Learning and Memory in Epilepsy (FLAME trial)

Abstract Background People with temporal lobe epilepsy (TLE) report significant problems with learning and memory. There are no effective therapies for combatting these problems in people with TLE, resulting in an unmet therapeutic need. The lack of treatment is, in part, due to a poor understanding...

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Bibliographic Details
Main Authors: Cheney J. G. Drew, Mark Postans, Cateno Petralia, Rachel McNamara, Philip Pallmann, Dave Gillespie, Lisa H. Evans, Nils Muhlert, Mia Winter, Khalid Hamandi, William P. Gray
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Pilot and Feasibility Studies
Subjects:
Temporal lobe epilepsy
Hippocampal sclerosis
Fluoxetine
Allocentric learning
Online Access:http://link.springer.com/article/10.1186/s40814-019-0474-x

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